Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

MABS441 Anti-WBP2 Antibody, clone 4C8H10

This Anti-WBP2 Antibody, clone 4C8H10 is validated for use in Western Blotting and Immunoprecipitation and Immunocytochemistry and Immunohistochemistry for the detection of WBP2.

Anti-WBP2 Antibody, clone 4C8H10 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Signaling, Apoptosis & Cancer Research Sub-Category: Growth Factors & Receptors Gene Symbol: WBP2 UniProt Number: Q969T9
MABS441
100 µL  
Purchase on Sigma-Aldrich

Speciální nabídky

Přehled

Replacement Information

Speciální nabídky

100% Performance Guaranteed

Tabulka spec. kláve

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWB, IP, ICC, IHCMPurifiedMonoclonal Antibody
Description
Catalogue NumberMABS441
DescriptionAnti-WBP2 Antibody, clone 4C8H10
Alternate Names
  • WW domain-binding protein 2
  • WBP-2
Background InformationWBP2 is a protein-protein interacting protein that binds to the WW domain of YAP1, WWP1 and WWP2 proteins. WW domain-containing proteins are found in most cells and play important roles in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. They are also upregulated in many cancers. WBP2 also interacts with the ubiquitin ligase proteins belonging to the NEDD4 family and appears to assist in the regulation of targeting proteins to proteasomes or lysosomes. Also in WBP2 knockout mice, the mice display abnormal brainstem and hearing development, indicating an important role in development as well.
References
Product Information
FormatPurified
PresentationPurified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationThis Anti-WBP2 Antibody, clone 4C8H10 is validated for use in Western Blotting and Immunoprecipitation and Immunocytochemistry and Immunohistochemistry for the detection of WBP2.
Key Applications
  • Western Blotting
  • Immunoprecipitation
  • Immunocytochemistry
  • Immunohistochemistry
Application NotesImmunohistochemistry Analysis: A representative lot detected WBP2 in breast cancer tissue at 1.25 ug/ml
Immunocytochemistry Analysis: A representative lot detected WBP2 in transfected HeLa cell fixed with 4% paraformaldehyde at 20 ug/ml
Immunoprecipitation Analysis: A representative lot immunoprecipitated transfected V5-WBP2 from HeLa cell
Biological Information
ImmunogenGST-tagged full length recombinant protein corresponding to Human WBP2.
Clone4C8H10
ConcentrationPlease refer to lot specific datasheet.
HostMouse
IsotypeIgG1κ
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • WBP2
Purification MethodProtein G Purified
UniProt Number
Molecular Weight~ 37 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in MDA-MB-231 cell lysate.

Western Blotting Analysis: 2.0 µg/mL of this antibody detected WBP2 in 10 µg of MDA-MB-231 cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
MABS441 04055977039542