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MABC94 Anti-Sphingosine 1-phosphate receptor 1 (S1P1) Antibody, clone 8B7.1

This Anti-Sphingosine 1-phosphate receptor 1 (S1P1) Antibody, clone 8B7.1 is validated for use in Western Blotting, IHC for the detection of Sphingosine 1-phosphate receptor 1 (S1P1).

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Apoptosis & Cancer Research Sub-Category: GPCR, cAMP/cGMP & Calcium Signaling Gene Symbol: S1PR1, CHEDG1, EDG1 UniProt Number: P21453
MABC94
100 µL  
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Tabulka spec. kláve

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, M, RWB, IHCMPurifiedMonoclonal Antibody
Description
Catalogue NumberMABC94
DescriptionAnti-Sphingosine 1-phosphate receptor 1 (S1P1) Antibody, clone 8B7.1
Alternate Names
  • Sphingosine 1-phosphate receptor 1
  • S1P receptor 1
  • S1P1
  • Endothelial differentiation G-protein coupled receptor 1
  • Sphingosine 1-phosphate receptor Edg-1
  • S1P receptor Edg-1
  • CD363
Background InformationSphingosine 1-phosphate receptor 1(S1PR1 or S1P1), otherwise known as EDG1, is a G-protein coupled receptor which is activated by lysosphingolipid sphingosine 1-phosphate (S1P) and lysophosphatidic acid (LPA). It is coupled to Gi-protein and MAP kinase signaling pathways, and may cooperate with other S1P receptors to regulate various cellular processes such as differentiation, actin remodeling, and migration. S1P1 is expressed in epithelial cells, fibroblasts, melanocytes, and smooth muscle cells.
References
Product Information
FormatPurified
Control
  • Mouse brain tissue lysate
PresentationPurified mouse monoclonal IgG2a supernatant in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationThis Anti-Sphingosine 1-phosphate receptor 1 (S1P1) Antibody, clone 8B7.1 is validated for use in Western Blotting, IHC for the detection of Sphingosine 1-phosphate receptor 1 (S1P1).
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application NotesWestern Blot Analysis: A 1:500 dilution from a representative lot detected Sphingosine 1-phosphate receptor 1 (S1P1) in human brain tissue lysate.

Immunohistochemistry Analysis: A 1:300 dilution from a representative lot detected Sphingosine 1-phosphate receptor 1 (S1P1) in rat choroid plexus tissue.
Biological Information
ImmunogenGST-tagged recombinant protein corresponding to mouse Sphingosine 1-phosphate receptor 1 (S1P1).
Clone8B7.1
HostMouse
IsotypeIgG2a
Species Reactivity
  • Human
  • Mouse
  • Rat
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • S1PR1
  • CHEDG1
  • EDG1
Purification MethodProtein G Purified
UniProt Number
Molecular Weight~40 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blot in mouse brain tissue lysate.

Western Blot Analysis: A 1:1,000 diluiton of this antibody detected Sphingosine 1-phosphate receptor 1 (S1P1) in 10 µg of mouse brain tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
MABC94 04053252694240

Documentation

Anti-Sphingosine 1-phosphate receptor 1 (S1P1) Antibody, clone 8B7.1 MSDS

Title

Safety Data Sheet (SDS) 

Anti-Sphingosine 1-phosphate receptor 1 (S1P1) Antibody, clone 8B7.1 Certificates of Analysis

TitleLot Number
Anti-Sphingosine 1-phosphate -2550060 2550060
Anti-Sphingosine 1-phosphate -2794956 2794956
Anti-Sphingosine 1-phosphate receptor 1 (S1P1), clone 8B7.1 - 2391198 2391198
Anti-Sphingosine 1-phosphate receptor 1 (S1P1), clone 8B7.1 - 2159660 2159660
Anti-Sphingosine 1-phosphate receptor 1 (S1P1), clone 8B7.1 - 2219401 2219401
Anti-Sphingosine 1-phosphate receptor 1 (S1P1), clone 8B7.1 - 2309338 2309338
Anti-Sphingosine 1-phosphate receptor 1 (S1P1), clone 8B7.1 - 3388466 3388466
Anti-Sphingosine 1-phosphate receptor 1 (S1P1), clone 8B7.1 - 3734542 3734542
Anti-Sphingosine 1-phosphate receptor 1 (S1P1), clone 8B7.1 - 3836590 3836590
Anti-Sphingosine 1-phosphate receptor 1 (S1P1), clone 8B7.1 - 3942155 3942155
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