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MABN316 Anti-SLC38A3 Antibody, clone 1A10.2

MABN316
100 µg  
Purchase on Sigma-Aldrich

Speciální nabídky

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Replacement Information

Speciální nabídky

Tabulka spec. kláve

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWB, IHCMPurifiedMonoclonal Antibody
Description
Catalogue NumberMABN316
DescriptionAnti-SLC38A3 Antibody, clone 1A10.2
Alternate Names
  • Sodium-coupled neutral amino acid transporter 3
  • N-system amino acid transporter 1
  • Na(+)-coupled neutral amino acid transporter 3
  • Solute carrier family 38 member 3
  • System N amino acid transporter 1
Background InformationThe sodium-coupled neutral amino acid transporter 3 (SLC38A3) protein is a sodium-dependent amino acid/proton exchanger (also called an antiporter or counter transporter) SLC38A3 mediates the electrogenic cotransport of glutamine and sodium ions in exchange for protons. SLC38A3 can also transport the amino acids histidine, asparagine and alanine in place of protons. Some evidence exists that SLC38A3 may mediate amino acid transport in either direction under particular physiological conditions such as homeostatic stress like that seen in acidosis, and SLC38A3 plays a role in nitrogen metabolism and synaptic transmission by regulating the levels of sodium and the stimulatory amino acid glutamine. SLC38A3 is localized to the cell membrane and is widely expressed in many tissues, including heart, liver, brain, and prostate.
References
Product Information
FormatPurified
PresentationPurified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-SLC38A3 Antibody, clone 1A10.2 | MABN316 is an antibody against SLC38A3 Antibody for use in Western Blotting, Immunohistochemistry.
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application NotesImmunohistochemistry Analysis: A 1:50 dilution from a representative lot detected SLC38A3 in human kidney tissue.
Biological Information
ImmunogenGST-tagged recombinant protein corresponding to human SLC38A3.
Clone1A10.2
ConcentrationPlease refer to lot specific datasheet.
HostMouse
IsotypeIgG2aκ
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • SLC38A3
  • G17
  • NAT1
  • SN1
  • SNAT3
Purification MethodProtein G Purified
UniProt Number
Molecular Weight~60 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in human kidney tissue lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected SLC38A3 in 10 µg of human kidney tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
MABN316 04055977127010