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ABF209 Anti-SLAMF2 (CD48 Antibody)

ABF209
100 µg  
Purchase on Sigma-Aldrich

Speciální nabídky

Přehled

Replacement Information

Speciální nabídky

Tabulka spec. kláve

Species ReactivityKey ApplicationsHostFormatAntibody Type
RWBRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABF209
DescriptionAnti-SLAMF2 (CD48 Antibody)
Alternate Names
  • Signaling lymphocytic activation molecule family member 2
  • CD48
  • BCM
  • BLAST1
  • MEM-102
  • CD48 antigen
  • B-lymphocyte activation marker BLAST-1
  • BCM1 surface antigen
  • Leukocyte antigen MEM-102
  • SLAMF
Background InformationThe signaling lymphocyte-activation molecule family member 2 (SLAMF2), also known as CD48, is a GPI-anchored protein that exists as both a soluble and membrane-associated form and is expressed in almost all leukocyte populations particularly in mitogen-stimulated human lymphocytes. SLAMF2 is a high-affinity ligand for SLAMF4, also known as 2B4, as well as a low-affinity ligand for CD2, and can thus can stimulate cells expressing these receptors. It has been shown to be an IL-3-induced activating receptor on eosinophils and is likely to be involved in promoting allergic inflammation. SLAMF2 is also thought to be involved in the IL-18/IL-18R signaling cascade in T and natural killer cells to produce interferon-gamma.
References
Product Information
FormatAffinity Purified
Control
  • Rat lung tissue lysate
PresentationPurified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-SLAMF2 (CD48 Antibody) is a highly specific rabbit polyclonal antibody, that targets CD48 & has been tested in western blotting.
Key Applications
  • Western Blotting
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to human SLAMF2.
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
Species Reactivity
  • Rat
Species Reactivity NoteDemonstrated to react with Rat. Predicted to react with Human based on immunogen design.
Antibody TypePolyclonal Antibody
Gene Symbol
  • CD48
  • SLAMF2
  • BCM1
Purification MethodAntigen Affinity Purified
UniProt Number
Molecular Weight~17 and ~28 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in rat lung tissue lysate.

Western Blotting Analysis: 2 µg/mL of this antibody detected SLAMF2 in 15 µg of rat lung tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
ABF209 04053252906978