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MABC662 Anti-RIPK2 Antibody, clone 1H10.1

MABC662
100 µL  
Purchase on Sigma-Aldrich

Speciální nabídky

Přehled

Replacement Information

Speciální nabídky

Tabulka spec. kláve

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWB, IHCMPurifiedMonoclonal Antibody
Description
Catalogue NumberMABC662
DescriptionAnti-RIPK2 Antibody, clone 1H10.1
Alternate Names
  • Receptor-interacting serine/threonine-protein kinase 2
  • CARD-containing interleukin-1 beta-converting enzyme-associated kinase
  • CARD-containing IL-1 beta ICE-kinase
  • RIP-like-interacting CLARP kinase
  • Receptor-interacting protein 2
  • RIP-2
  • Tyrosine-protein kinase RIPK2
Background InformationReceptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1; EC 2.7.10.2; UniProt O43353; also known as Receptor-interacting protein 2, CARD-carrying kinase, CARD-containing IL-1 beta ICE-kinase, CARD-containing interleukin-1 beta-converting enzyme-associated kinase, Growth-inhibiting gene 30, Receptor-interacting protein-like interacting caspase-like apoptosis regulatory protein kinase, RIP-2, RIP-like interacting CLARP kinase, Tyrosine-protein kinase RIPK2) is encoded by the RIPK2 (also known as CARD3, CARDIAK, CCK, GIG30, RICK, RIP2) gene (Gene ID 8767) in human. RIPK2 is a dual-specificity kinase that exhibits both serine/threonine as well as tyrosine kinase activities. RIPK2 participates in transducing cellular inflammatory response by propagating signaling downstream of the intracellular peptidoglycan sensors NOD1 and NOD2.
References
Product Information
FormatPurified
PresentationPurified mouse monoclonal IgMκ antibody in PBS with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-RIPK2 Antibody, clone 1H10.1 is an antibody against RIPK2 for use in Western Blotting and Immunohistochemistry.
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application NotesImmunohistochemistry Analysis: A 1:50 dilution from a representative lot detected RIPK2 in human prostate and human placenta tissue.
Biological Information
ImmunogenGST-tagged recombinant protein corresponding to human RIPK2.
Clone1H10.1
ConcentrationPlease refer to lot specific datasheet.
HostMouse
SpecificityExpected to react with both isoforms.
IsotypeIgMκ
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • RIPK2
  • CARDIAK
  • RICK
  • RIP2
UniProt Number
Molecular Weight~60 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in human placenta tissue lysate.

Western Blotting Analysis: A 1:500 dilution of this antibody detected RIPK2 in 10 µg of human placenta tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
MABC662 04055977170672

Documentation

Anti-RIPK2 Antibody, clone 1H10.1 MSDS

Title

Safety Data Sheet (SDS) 

Anti-RIPK2 Antibody, clone 1H10.1 Certificates of Analysis

TitleLot Number
Anti-RIPK2, Clone 1H10.1 - 3987753 3987753
Anti-RIPK2, Clone 1H10.1 - 4187067 4187067
Anti-RIPK2, clone 1H10.1 - 3419570 3419570
Anti-RIPK2, clone 1H10.1 -Q2573208 Q2573208

Technical Info

Title
Characterization of Estrogen Receptor α Phosphorylation Sites in Breast Cancer Tissue Using the SNAP i.d® 2.0 System
White Paper: Further considerations of antibody validation and usage.