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MABC290 Anti-PDL-1/CD274 Antibody, clone 3F2.1

Anti-PDL-1/CD274 Antibody, clone 3F2.1 is an antibody against PDL-1/CD274 for use in western blotting & IHC.

Anti-PDL-1/CD274 Antibody, clone 3F2.1 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Apoptosis & Cancer Research Sub-Category: Apoptosis - Additional Gene Symbol: CD274, B7H1, PDCD1L1, PDCD1LG1, PDL1 UniProt Number: Q9NZQ7
MABC290
100 µg  
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Tabulka spec. kláve

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWB, IHCMPurifiedMonoclonal Antibody
Description
Catalogue NumberMABC290
DescriptionAnti-PDL-1/CD274 Antibody, clone 3F2.1
Alternate Names
  • Programmed cell death 1 ligand 1
  • PD-L1
  • PDCD1 ligand 1
  • Programmed death ligand 1
  • B7 homolog 1
  • B7-H1
  • CD274
  • PDL-1
Background InformationProgrammed cell death 1 ligand 1 (PDL-1) is a B7 related protein belonging to the BTN/MOG family. PDL-1 is essential for T-cell proliferation and production of IL10 and IFNG. PDL-1 reduces the secretion of IL-2 and IL-10 from memory T cells by inhibiting cell-mediated immune responses. PDL-1 may be involved in reducing allogenic CD4+ memory T-cell responses to endothelial cells. PDL-1 is highly expressed in heart, skeletal muscle, placenta, and lung and weakly expressed in thymus, spleen, kidney, and liver.
Product Information
FormatPurified
PresentationPurified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-PDL-1/CD274 Antibody, clone 3F2.1 is an antibody against PDL-1/CD274 for use in western blotting & IHC.
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application NotesImmunohistochemistry Analysis: A 1:50 and 1:500 dilution from a representative lot detected PDL-1/CD274 in human tonsil and skeletal muscle tissue, respectively.
Biological Information
ImmunogenGST-tagged recombinant protein corresponding to the extracellular domain of human PDL-1/CD274.
Epitopeextracellular domain
Clone3F2.1
Concentration1 mg/mL
HostMouse
IsotypeIgG1κ
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • CD274
  • B7H1
  • PDCD1L1
  • PDCD1LG1
  • PDL1
Purification MethodProtein G Purified
UniProt Number
Molecular Weight~40 kDa observed. The calculated molecular weight is 33 kDa; however, this protein may be observed at higher molecular weights to due to heavy glycosylation.
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in human skeletal muscle tissue.

Western Blotting Analysis: 1 µg/mL of this antibody detected PDL-1/CD274 in 10 µg of human skeletal muscle tissue.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Global Trade Item Number
Katalogové číslo GTIN
MABC290 04053252975592