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AB9478 Anti-P2Y6 Receptor Antibody

AB9478
50 µg  
Purchase on Sigma-Aldrich

Speciální nabídky

Přehled

Replacement Information

Speciální nabídky

Tabulka spec. kláve

Species ReactivityKey ApplicationsHostFormatAntibody Type
HICC, IH(P)RbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberAB9478
Brand Family Chemicon®
Trade Name
  • Chemicon
DescriptionAnti-P2Y6 Receptor Antibody
References
Product Information
FormatAffinity Purified
PresentationAffinity purified immunoglobulin. Liquid in PBS, pH 7.7 with 0.01% sodium azide.
Quality LevelMQ100
Applications
ApplicationThis Anti-P2Y6 Receptor Antibody is validated for use in IC, IH(P) for the detection of P2Y6 Receptor.
Key Applications
  • Immunocytochemistry
  • Immunohistochemistry (Paraffin)
Application NotesImmunohistochemistry on formalin fixed paraffin embedded tissue sections.

Immunocytochemistry on acetone fixed cells.

Optimal working dilutions must be determined by the end user.
Biological Information
ImmunogenSynthetic peptide from the C-terminal domain of human P2Y6. The immunogen has 100% homology with rat.
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
SpecificityRecognizes P2Y6.
Species Reactivity
  • Human
Antibody TypePolyclonal Antibody
Entrez Gene Number
Entrez Gene SummaryThe product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is responsive to UDP, partially responsive to UTP and ADP, and not responsive to ATP. Four transcript variants encoding the same isoform have been identified for this gene.
Gene Symbol
  • P2RY6
  • P2Y6
  • MGC15335
  • ORFNames=PP2891
UniProt Number
UniProt SummaryFUNCTION: SwissProt: Q15077 # Receptor for extracellular UDP > UTP > ATP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system.
SIZE: 328 amino acids; 36429 Da
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
SIMILARITY: SwissProt: Q15077 ## Belongs to the G-protein coupled receptor 1 family.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Availability by Geography
  • This product is not available for sale in Japan.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintain at -70°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
Packaging Information
Material Size50 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
AB9478 04053252673085