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AB15138 Anti-Nogo Receptor Antibody

Anti-Nogo Receptor Antibody detects level of Nogo Receptor & has been published & validated for use in WB, IH.

Anti-Nogo Receptor Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Growth Cones & Axon Guidance UniProt Number: Q99PI8
AB15138
100 µg  
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Tabulka spec. kláve

Species ReactivityKey ApplicationsHostFormatAntibody Type
M, R, HWB, IHCRbPurifiedPolyclonal Antibody
Description
Catalogue NumberAB15138
DescriptionAnti-Nogo Receptor Antibody
Alternate Names
  • Reticulon-4 receptor
  • Nogo receptor
  • NgR
  • Nogo-66 receptor
  • Nogor
  • Rtn4r
Background InformationAxons are essential for neuronal communication but they do not regenerate after injury to the adult mammalian brain or spinal cord. Failed regeneration is due in part to the production of a potent axonal growth inhibitor, Nogo, by myelinating cells. The finding of a high affinity axonal receptor for the extracellular domain of Nogo provides the first insight into the basis of Nogo action. Disrupting the interaction of Nogo with the Nogo-66 receptor may facilitate axonal regeneration in vivo. The protein is dubbed the Nogo receptor because it binds with several other proteins that block neural growth. It is found to be ubiquitous in the brain and spinal cord.
References
Product Information
FormatPurified
Control
  • Mouse cerebellum lysate
PresentationPurified in PBS with 0.1% NaN3
Quality LevelMQ100
Applications
ApplicationAnti-Nogo Receptor Antibody detects level of Nogo Receptor & has been published & validated for use in WB, IH.
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application NotesNon-Lot Specific Tested Application 1:
Immunohistochemistry: Working dilutions of 1:50-1:500 in rat brain and spinal cord (paraffin embedded)
Biological Information
ImmunogenRecombinant protein.
EpitopeMature Form
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
SpecificityCat. # AB15138 recognizes the mature form of Nogo Receptor.
Species Reactivity
  • Mouse
  • Rat
  • Human
Species Reactivity NoteMouse and rat. May react with human and primate based on sequence homology. Reactivity with other species has not been determined.
Antibody TypePolyclonal Antibody
Entrez Gene Number
Purification MethodProtein A Purfied
UniProt Number
Molecular Weight~50.9 kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceRoutinely tested on mouse cerebellum lysate.
Lot Specific Tested Application 1: Western Blot
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintain at 2-8°C in undiluted aliquots for up to 1 year after date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
AB15138 04053252625527

Documentation

Anti-Nogo Receptor Antibody MSDS

Title

Safety Data Sheet (SDS) 

Anti-Nogo Receptor Antibody Certificates of Analysis

TitleLot Number
Anti-Nogo Receptor - 1977609 1977609
Anti-Nogo Receptor - 3172613 3172613
Anti-Nogo Receptor - 3498495 3498495
Anti-Nogo Receptor - 3548398 3548398
Anti-Nogo Receptor - 3768098 3768098
Anti-Nogo Receptor - LV1647009 LV1647009
Anti-Nogo Receptor - NG1552292 NG1552292
Anti-Nogo Receptor - NG1832151 NG1832151
Anti-Nogo Receptor - NG1925396 NG1925396
Anti-Nogo Receptor -2507757 2507757
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