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ST1652 Anti-MVK Mouse mAb (2C5)

Anti-MVK Mouse mAb (2C5) MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Anti-Mevalonate Kinase

ST1652
  
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Tabulka spec. kláve

Host
M
Description
Overview

This product has been discontinued.





Recognizes the MVK protein in human salivary gland tissue.
Catalogue NumberST1652
Brand Family Calbiochem®
SynonymsAnti-Mevalonate Kinase
Application Data
Detection of human MVK by immunoblotting. Sample: Whole cell lysate from 293T cells transfected with partial recombinant MVK (lane 1) and from non-transfected 293T cells (lane 2). Primary antibody: Anti-MVK Mouse mAb (2C5) (Cat. No. ST1652) (1-5 µg/ml). Detection: chemiluminescence.

Detection of human MVK by staining paraffin sections. Sample: Formalin-fixed, paraffin-embedded human salivary gland tissue. Primary antibody: Anti-MVK Mouse mAb (2C5) (Cat. No. ST1652) (3 µg/ml). Detection: colorimetric (DAB).
References
Product Information
FormLiquid
FormulationIn PBS, pH 7.2.
Negative control293T cells
Positive controlHuman salivary gland tissue
PreservativeNone
Applications
Key Applications Enzyme-Linked Immunosorbent Assay
Immunoblotting (Western Blotting)
Paraffin Sections
Application NotesELISA (see comments)
Immunoblotting (1-5 µg/ml)
Paraffin Sections (3 µg/ml)
Application CommentsFor ELISA, this antibody can be used as the capture antibody; recommended concentration is 10 ng/ml, 1 µg/well, 100 µl total volume. Variables associated with assay conditions will dictate the proper working dilution.
Biological Information
ImmunogenA recombinant polypeptide corresponding to amino acids of 297-397 human MVK, expressed as a GST fusion protein
Clone2C5
HostMouse
IsotypeIgG2a
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Blue Ice Only
Toxicity Standard Handling
Storage -20°C
Avoid freeze/thaw Avoid freeze/thaw
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
ST1652 0

Documentation

Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision10-November-2010 RFH
SynonymsAnti-Mevalonate Kinase
ApplicationELISA (see comments)
Immunoblotting (1-5 µg/ml)
Paraffin Sections (3 µg/ml)
Application Data
Detection of human MVK by immunoblotting. Sample: Whole cell lysate from 293T cells transfected with partial recombinant MVK (lane 1) and from non-transfected 293T cells (lane 2). Primary antibody: Anti-MVK Mouse mAb (2C5) (Cat. No. ST1652) (1-5 µg/ml). Detection: chemiluminescence.

Detection of human MVK by staining paraffin sections. Sample: Formalin-fixed, paraffin-embedded human salivary gland tissue. Primary antibody: Anti-MVK Mouse mAb (2C5) (Cat. No. ST1652) (3 µg/ml). Detection: colorimetric (DAB).
DescriptionPurified mouse monoclonal antibody. Recognizes the MVK protein.
BackgroundThis gene encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash. Two transcript variants that encode the same protein have been found for this gene.
HostMouse
ImmunogenA recombinant polypeptide corresponding to amino acids of 297-397 human MVK, expressed as a GST fusion protein
Clone2C5
IsotypeIgG2a
Specieshuman
Positive controlHuman salivary gland tissue
Negative control293T cells
FormLiquid
FormulationIn PBS, pH 7.2.
PreservativeNone
CommentsFor ELISA, this antibody can be used as the capture antibody; recommended concentration is 10 ng/ml, 1 µg/well, 100 µl total volume. Variables associated with assay conditions will dictate the proper working dilution.
Storage Avoid freeze/thaw
-20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
Toxicity Standard Handling