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438192 Anti-LRP, Light Chain Mouse mAb (5A6)

This Anti-LRP, Light Chain Mouse mAb (5A6) is validated for use in Frozen Sections, Immunoblotting, Paraffin Sections for the detection of LRP, Light Chain.

Anti-LRP, Light Chain Mouse mAb (5A6) MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Anti-Low Density Lipoprotein Receptor-Related Protein

438192
Purchase on Sigma-Aldrich

Přehled

Replacement Information

Tabulka spec. kláve

Species ReactivityHostAntibody Type
H, M, RbMMonoclonal Antibody

Products

Katalogové čísloBalení ks/bal.
438192-100UG Plastová ampulka 100 μg
Description
OverviewRecognizes the ~85 kDa LRP protein.
Catalogue Number438192
Brand Family Calbiochem®
SynonymsAnti-Low Density Lipoprotein Receptor-Related Protein
Application Data
Detection of light chain LRP by immunoblotting. Samples: Soluble LRP at 500 ng (lane 1) and 50 ng (lane 2) with prestained standard (lane 3). Primary antibody: Anti-LRP, Light Chain Mouse mAb (5A6) (Cat. No. 438192) (1 µg/ml). Detection: chemiluminescence.
References
ReferencesMikhailenko, I., et al. 2001. J. Biol. Chem. 276, 39484.
Rebeck, W.G., et al. 2001. Mol. Brain Res. 87, 238.
Coukos, G., et al. 1994. Am. J. Pathol. 144, 383.
Daugherty, A., and Rateri, D.L. 1994. Arterioscler Thromb. 14, 2017.
Strickland, D.K., et al. 1990. J. Biol. Chem. 265, 17401.
Product Information
FormLiquid
FormulationIn 100 mM NaCl, 50 mM sodium phosphate, 1 mM EDTA, pH 6.6.
PreservativeNone
Quality LevelMQ100
Applications
Application ReferencesParaffin Sections Coukos, G., et al. 1994. Am. J. Pathol. 144, 383. Daugherty, A., and Rateri, D.L. 1994. Arterioscler Thromb. 14, 2017. Rebeck, G.W., et al. 1993. Neuron 11, 575.
Key Applications Frozen Sections
Immunoblotting (Western Blotting)
Paraffin Sections
Application NotesFrozen Sections (1-5 µg/ml)
Immunoblotting (1-5 µg/ml)
Paraffin Sections (1-5 µg/ml, see application references)
Application CommentsVariables associated with assay conditions will dictate the proper working dilution.
Biological Information
Immunogenpurified, human placenta LRP
ImmunogenHuman
Clone5A6
HostMouse
IsotypeIgG₂
Species Reactivity
  • Human
  • Mouse
  • Rabbit
Antibody TypeMonoclonal Antibody
Concentration Label Please refer to vial label for lot-specific concentration
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Standard Handling
Storage -20°C
Avoid freeze/thaw Avoid freeze/thaw
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
438192-100UG 07790788050283

Documentation

Anti-LRP, Light Chain Mouse mAb (5A6) MSDS

Title

Safety Data Sheet (SDS) 

Anti-LRP, Light Chain Mouse mAb (5A6) Certificates of Analysis

TitleLot Number
438192

References

Přehled odkazů
Mikhailenko, I., et al. 2001. J. Biol. Chem. 276, 39484.
Rebeck, W.G., et al. 2001. Mol. Brain Res. 87, 238.
Coukos, G., et al. 1994. Am. J. Pathol. 144, 383.
Daugherty, A., and Rateri, D.L. 1994. Arterioscler Thromb. 14, 2017.
Strickland, D.K., et al. 1990. J. Biol. Chem. 265, 17401.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision06-September-2008 JSW
SynonymsAnti-Low Density Lipoprotein Receptor-Related Protein
ApplicationFrozen Sections (1-5 µg/ml)
Immunoblotting (1-5 µg/ml)
Paraffin Sections (1-5 µg/ml, see application references)
Application Data
Detection of light chain LRP by immunoblotting. Samples: Soluble LRP at 500 ng (lane 1) and 50 ng (lane 2) with prestained standard (lane 3). Primary antibody: Anti-LRP, Light Chain Mouse mAb (5A6) (Cat. No. 438192) (1 µg/ml). Detection: chemiluminescence.
DescriptionPurified mouse monoclonal antibody. Recognizes the ~85 kDa LRP light chain protein under non-reducing conditions.
BackgroundLRP (Low Density Lipoprotein Receptor-Related Protein) contributes to the pathology of Alzheimer's disease by influencing both the production and clearance of the β-amyloid peptide.
HostMouse
Immunogen speciesHuman
Immunogenpurified, human placenta LRP
Clone5A6
IsotypeIgG₂
Specieshuman, mouse, rabbit
FormLiquid
FormulationIn 100 mM NaCl, 50 mM sodium phosphate, 1 mM EDTA, pH 6.6.
Concentration Label Please refer to vial label for lot-specific concentration
PreservativeNone
CommentsVariables associated with assay conditions will dictate the proper working dilution.
Storage Avoid freeze/thaw
-20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
Toxicity Standard Handling
ReferencesMikhailenko, I., et al. 2001. J. Biol. Chem. 276, 39484.
Rebeck, W.G., et al. 2001. Mol. Brain Res. 87, 238.
Coukos, G., et al. 1994. Am. J. Pathol. 144, 383.
Daugherty, A., and Rateri, D.L. 1994. Arterioscler Thromb. 14, 2017.
Strickland, D.K., et al. 1990. J. Biol. Chem. 265, 17401.
Application referencesParaffin Sections Coukos, G., et al. 1994. Am. J. Pathol. 144, 383. Daugherty, A., and Rateri, D.L. 1994. Arterioscler Thromb. 14, 2017. Rebeck, G.W., et al. 1993. Neuron 11, 575.