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MAB2153 Anti-E-Selectin Antibody, lectin domain, clone UZ4

MAB2153
100 µg  
Purchase on Sigma-Aldrich

Speciální nabídky

Přehled

Replacement Information

Speciální nabídky

Tabulka spec. kláve

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, MELISA, FC, IP, WB, FUNCRPurifiedMonoclonal Antibody
Description
Catalogue NumberMAB2153
Brand Family Chemicon®
Trade Name
  • Chemicon
DescriptionAnti-E-Selectin Antibody, lectin domain, clone UZ4
Alternate Names
  • CD62E
  • ELAM-1
References
Product Information
FormatPurified
Quality LevelMQ100
Applications
ApplicationAnti-E-Selectin Antibody, lectin domain, clone UZ4 is an antibody against E-Selectin for use in ELISA, FC, IP & WB.
Key Applications
  • ELISA
  • Flow Cytometry
  • Immunoprecipitation
  • Western Blotting
  • Affects Function
Applications Not Recommended
  • Immunohistochemistry
Biological Information
ImmunogenIgM
Epitopelectin domain
CloneUZ4
HostRat
Species Reactivity
  • Human
  • Mouse
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Entrez Gene SummaryThe endothelial leukocyte adhesion molecule-1 is expressed by cytokine-stimulated endothelial cells. It is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. This gene is present in single copy in the human genome and contains 14 exons spanning about 13 kb of DNA. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis.
Gene Symbol
  • SELE
  • LECAM2
  • ESEL
  • ELAM
  • ELAM-1
  • CD62E
  • ELAM1
UniProt Number
UniProt SummaryFUNCTION: SwissProt: P16581 # Expressed on cytokine induced endothelial cells and mediates their binding to leukocytes. The ligand recognized by ELAM-1 is sialyl-lewis X (alpha(1->3)fucosylated derivatives of polylactosamine that are found at the nonreducing termini of glycolipids).
SIZE: 610 amino acids; 66655 Da
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
SIMILARITY: SwissProt: P16581 ## Belongs to the selectin/LECAM family. & Contains 1 C-type lectin domain. & Contains 1 EGF-like domain. & Contains 6 Sushi (CCP/SCR) domains.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
MAB2153 04053252576430

Documentation

Anti-E-Selectin Antibody, lectin domain, clone UZ4 MSDS

Title

Safety Data Sheet (SDS) 

Anti-E-Selectin Antibody, lectin domain, clone UZ4 Certificates of Analysis

TitleLot Number
RAT ANTI-E-SELECTIN 2479817
RAT ANTI-E-SELECTIN MONOCLONAL ANTIBODY - 2111257 2111257
RAT ANTI-E-SELECTIN MONOCLONAL ANTIBODY - 2462906 2462906
RAT ANTI-E-SELECTIN - 3484047 3484047
RAT ANTI-E-SELECTIN -2666614 2666614
RAT ANTI-E-SELECTIN -2751153 2751153
RAT ANTI-E-SELECTIN -2766374 2766374
RAT ANTI-E-SELECTIN MONOCLONAL ANTIBODY 2981017
RAT ANTI-E-SELECTIN MONOCLONAL ANTIBODY - 3174772 3174772

Data Sheet

Title
RAT ANTI-E-SELECTIN MONOCLONAL ANTIBODY