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MABN353 Anti-DOCK8 Antibody, clone 10C3.2

Anti-DOCK8 Antibody, clone 10C3.2 is an antibody against DOCK8 for use in Western Blotting, Flow Cytometry.

Anti-DOCK8 Antibody, clone 10C3.2 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Developmental Signaling Gene Symbol: DOCK8 UniProt Number: Q8NF50
MABN353
100 µg  
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Tabulka spec. kláve

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWB, FCMPurifiedMonoclonal Antibody
Description
Catalogue NumberMABN353
DescriptionAnti-DOCK8 Antibody, clone 10C3.2
Alternate Names
  • DOCK8
  • Dedicator of cytokinesis protein 8
Background InformationDedicator of cytokinesis protein 8 (also known as 1200017A24Rik or Epididymis luminal protein 205) is encoded by the DOCK8 gene (also known as HEL-205, MRD2, ZIR8) in human (NCBI Gene ID 81704). DOCK8 is a cytosolic scaffolding protein involved in cytoskeletal rearrangement and cell migration. DOCK8 deficiency due to genetic mutations result in combined immune deficiency, historically diagnosed as an atypical form of hyper-IgE syndrome (HIES) or autosomal recessive HIES, which remains to be the focus of ongoing DOCK8 research activities. (PMIDn20864884). Clone 10C3.2 detects an internal epitope within the C-terminal half of the DOCK8 protein (UniProt Q8NF50).
References
Product Information
FormatPurified
PresentationPurified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ300
Applications
ApplicationAnti-DOCK8 Antibody, clone 10C3.2 is an antibody against DOCK8 for use in Western Blotting, Flow Cytometry.
Key Applications
  • Western Blotting
  • Flow Cytometry
Application NotesFlow Cytometry Analysis: 2.5 µg of this antibody from a representative lot detected DOCK8 in cycling T cells (Dr's. Qian Zhang and Helen Su).
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to human DOCK8.
Clone10C3.2
ConcentrationPlease refer to lot specific datasheet.
HostMouse
IsotypeIgG1κ
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • DOCK8
Purification MethodProtein G Purified
UniProt Number
Molecular Weight~230 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in EBV transformed B lymphoblastoid cell lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected DOCK8 in 10 µg of EBV transformed B lymphoblastoid cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
MABN353 04055977162714