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195111 Anti-BACE1, C-Terminal (485-501) Rabbit pAb

Anti-BACE1, C-Terminal (485-501), rabbit polyclonal, recognizes both the immature and mature forms of the BACE1. It is validated for WB, IF, IHC, IP, and RIA.

Anti-BACE1, C-Terminal (485-501) Rabbit pAb MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Anti-B690

195111
  
Purchase on Sigma-Aldrich

Přehled

Replacement Information

Tabulka spec. kláve

Species ReactivityHostAntibody Type
H, M, RRbPolyclonal Antibody
Description
Overview

This product has been discontinued.



Recognizes both the immature and mature forms of the BACE1 protein.
Catalogue Number195111
Brand Family Calbiochem®
SynonymsAnti-B690
References
ReferencesYan, R., et al. 2001. J. Biol. Chem. 276, 36788.
Product Information
FormLiquid
FormulationUndiluted serum.
PreservativeNone
Quality LevelMQ100
Applications
Key Applications Immunoblotting (Western Blotting)
Immunofluorescence
Immunohistochemistry
Immunoprecipitation
Radioimmunoassay
Application NotesImmunoblotting (1:500-1:1000)
Immunofluorescence (1:200)
Immunohistochemistry (see comments)
Immunoprecipitation (3 µl/reaction)
Radioimmunoassay (3-5 µl/reaction)
Application CommentsThis antibody is also reported to work for immunohistochemistry. Variables associated with assay conditions will dictate the optimal working dilution.
Biological Information
Immunogena synthetic peptide (CLRQQHDDFADDISLLK) corresponding to amino acids 485-501 of human BACE1, conjugated to KLH
ImmunogenHuman
HostRabbit
IsotypeIgG
Species Reactivity
  • Human
  • Mouse
  • Rat
Antibody TypePolyclonal Antibody
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Standard Handling
Storage -20°C
Avoid freeze/thaw Avoid freeze/thaw
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
195111 0

Documentation

Anti-BACE1, C-Terminal (485-501) Rabbit pAb MSDS

Title

Safety Data Sheet (SDS) 

Anti-BACE1, C-Terminal (485-501) Rabbit pAb Certificates of Analysis

TitleLot Number
195111

References

Přehled odkazů
Yan, R., et al. 2001. J. Biol. Chem. 276, 36788.

Brochure

Title
Alzheimer's Disease Brochure & Technical Guide
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision27-June-2007 RFH
SynonymsAnti-B690
ApplicationImmunoblotting (1:500-1:1000)
Immunofluorescence (1:200)
Immunohistochemistry (see comments)
Immunoprecipitation (3 µl/reaction)
Radioimmunoassay (3-5 µl/reaction)
DescriptionRabbit polyclonal antibody supplied as undiluted serum. Recognizes both the immature and mature forms of BACE1.
Backgroundβ-secretase has been identified as a novel membrane-bound aspartyl protease named BACE1 (β-site amyloid precursor protein cleaving enzyme 1). It is one of two endopeptidases that cleave the β-amyloid precursor protein (APP) resulting in the accumulation of the β-amyloid deposits involved in the development of Alzheimer's disease.
HostRabbit
Immunogen speciesHuman
Immunogena synthetic peptide (CLRQQHDDFADDISLLK) corresponding to amino acids 485-501 of human BACE1, conjugated to KLH
IsotypeIgG
Specieshuman, mouse, rat
FormLiquid
FormulationUndiluted serum.
PreservativeNone
CommentsThis antibody is also reported to work for immunohistochemistry. Variables associated with assay conditions will dictate the optimal working dilution.
Storage Avoid freeze/thaw
-20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
Toxicity Standard Handling
ReferencesYan, R., et al. 2001. J. Biol. Chem. 276, 36788.