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ABS184 Anti-AMPylated Tyrosine Antibody

Anti-AMPylated Tyrosine Antibody detects level of AMPylated Tyrosine & has been published & validated for use in Western Blotting.

Anti-AMPylated Tyrosine Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Signaling Research Sub-Category: General Post-translation Modification
ABS184
100 µL  
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Tabulka spec. kláve

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWBRbSerumPolyclonal Antibody
Description
Catalogue NumberABS184
DescriptionAnti-AMPylated Tyrosine Antibody
Alternate Names
  • AMPylated Tyrosine
Background InformationAMPylation is a reversible post-translational modification in which adenosine monophosphate (AMP) derived from ATP is added to threonine and tyrosine (and possibly serine) residues on target proteins. This modification is created by proteins containing Fic (filamentation induced by cyclic adenosine monophosphate) domains, which are present in both prokaryotic and eukaryotic cells. In mammals, the HYPE protein is the most widely known Fic-containing protein and the precise function of its AMPylated targets is not yet clear. However, bacterial cells possess numerous Fic-domain proteins that modify and disable protein targets in host cells, thereby suppressing signaling pathways and increasing the robustness of pathogenic infections. The Vibrio parahaemolyticus VopS protein, for instance, disrupts the function of Rho guanine triphosphatases, and eventually disrupts the actin cytoskeleton.
References
Product Information
FormatSerum
Control
  • Rac1, AMPylated in vitro
PresentationRabbit polyclonal serum containing 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-AMPylated Tyrosine Antibody detects level of AMPylated Tyrosine & has been published & validated for use in Western Blotting.
Key Applications
  • Western Blotting
Biological Information
HostRabbit
SpecificityThis antibody recognizes AMPylated Tyrosines.
IsotypeIgG
Species Reactivity
  • Human
Species Reactivity NoteDemonstrated to react with Human. Broad species reactivity expected, as AMPylation is evolutionarily conserved.
Antibody TypePolyclonal Antibody
Purification MethodUnpurified
Molecular Weight~21 kDa observed. Molecular weights will vary based on the protein being AMPylated.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blot in Rac1, AMPylated in vitro.

Western Blot Analysis: A 1:1,000 dilution of this antibody detected AMPylated Tyrosine on 10 ng of Rac1, AMPylated in vitro.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
ABS184 04053252439247

Documentation

Anti-AMPylated Tyrosine Antibody MSDS

Title

Safety Data Sheet (SDS) 

Anti-AMPylated Tyrosine Antibody Certificates of Analysis

TitleLot Number
Anti-AMPylated Tyrosine - 2450771 2450771
Anti-AMPylated Tyrosine - 2341112 2341112
Anti-AMPylated Tyrosine - 2512049 2512049
Anti-AMPylated Tyrosine - 3216004 3216004
Anti-AMPylated Tyrosine - 3839094 3839094
Anti-AMPylated Tyrosine - Q2005661 Q2005661
Anti-AMPylated Tyrosine -2890952 2890952
Anti-AMPylated Tyrosine Polyclonal Antibody 3041062
Anti-AMPylated Tyrosine Polyclonal Antibody 3091980
Anti-AMPylated Tyrosine Polyclonal Antibody 2929154

Brochure

Title
New Products: Volume 3, 2012