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422751 Anti-ADAM10 (735-749) Rabbit pAb

Anti-ADAM10 (735-749) Rabbit pAb MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Anti-Kuz

422751
  
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Přehled

Replacement Information

Tabulka spec. kláve

Host
Rb
Description
Overview

This product has been discontinued.



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Recognizes the ~98 and ~105 kDa bands corresponding to full length ADAM1O in transfected CHO-K cells, the ~60 kDa cleaved mature protein and the ~30 kDa degradation product.
  • Antibody Target Gene Symbol: ADAM10
  • Target Synonym: 1700031C13Rik, AD10, ALPHA SECRETASE, CD156c, DISINTEGRIN-METALLOPROTEASE, HsT18717, Kuz, KUZBANIAN, MADM
  • Entrez Gene Name: ADAM metallopeptidase domain 10
  • Hu Entrez ID: 102 (Related Antibodies: PC528)
  • Mu Entrez ID: 11487
  • Rat Entrez ID: 29650
    		•
    Catalogue Number422751
    Brand Family Calbiochem®
    SynonymsAnti-Kuz
    References
    ReferencesQi, H., et al. 1999. Science 283, 91.
    Pan, D. and Rubin, G.M. 1997. Cell 90, 271.
    Rosendahl, M.S., et al. 1997. J. Biol. Chem. 272, 24588.
    Product Information
    FormLiquid
    FormulationUndiluted serum.
    Positive controlADAM10-transfected CHO cells
    PreservativeNone
    Applications
    Key Applications Immunoblotting (Western Blotting)
    Application NotesImmunoblotting (1:2000)
    Application CommentsVariables associated with assay conditions will dictate the optimal working dilution.
    Biological Information
    Immunogena synthetic peptide [(C)RQRPRESYQMGHMRR] corresponding to amino acids 735-749 of mouse ADAM10
    ImmunogenMouse
    HostRabbit
    IsotypeIgG
    Physicochemical Information
    Dimensions
    Materials Information
    Toxicological Information
    Safety Information according to GHS
    Safety Information
    Product Usage Statements
    Storage and Shipping Information
    Ship Code Dry Ice Only
    Toxicity Standard Handling
    Storage -20°C
    Avoid freeze/thaw Avoid freeze/thaw
    Do not freeze Ok to freeze
    Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
    Packaging Information
    Transport Information
    Supplemental Information
    Specifications
    Global Trade Item Number
    Katalogové číslo GTIN
    422751 0

    Documentation

    Anti-ADAM10 (735-749) Rabbit pAb Certificates of Analysis

    TitleLot Number
    422751

    References

    Přehled odkazů
    Qi, H., et al. 1999. Science 283, 91.
    Pan, D. and Rubin, G.M. 1997. Cell 90, 271.
    Rosendahl, M.S., et al. 1997. J. Biol. Chem. 272, 24588.
    Data Sheet

    Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

    Revision18-October-2007 JSW
    SynonymsAnti-Kuz
    ApplicationImmunoblotting (1:2000)
    DescriptionRabbit polyclonal antibody supplied as undiluted serum. Recognizes the ~98 and ~105 kDa bands corresponding to full length ADAM10, the ~60 kDa cleaved mature protein, and the ~30 kDa degradation product.
    BackgroundKUZ (ADAM10) is a disintegrin metallo-protease in the family of mammalian ADAM. ADAM10 was recently demonstrated to cleave TNFα, notch and its ligand delta. The genes encoding human, mouse, and bovine ADAM10 were recently cloned and designated as ADAM 10, kuzbanian (KUZ), and MADM, respectively. ADAM10 mRNA is expressed in a variety of human and bovine tissues.
    HostRabbit
    Immunogen speciesMouse
    Immunogena synthetic peptide [(C)RQRPRESYQMGHMRR] corresponding to amino acids 735-749 of mouse ADAM10
    IsotypeIgG
    Specieshamster, human, mouse
    Positive controlADAM10-transfected CHO cells
    FormLiquid
    FormulationUndiluted serum.
    PreservativeNone
    CommentsVariables associated with assay conditions will dictate the optimal working dilution.
    Storage Avoid freeze/thaw
    -20°C
    Do Not Freeze Ok to freeze
    Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
    Toxicity Standard Handling
    ReferencesQi, H., et al. 1999. Science 283, 91.
    Pan, D. and Rubin, G.M. 1997. Cell 90, 271.
    Rosendahl, M.S., et al. 1997. J. Biol. Chem. 272, 24588.