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05-23-0101 Angiotensin II, Human - CAS 4474-91-3 - Calbiochem

Plays an important role in the regulation of blood pressure.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: DRVYIHPF

Primary Target: adenylate cyclase activity
05-23-0101
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Tabulka spec. kláve

CAS #Empirical Formula
4474-91-3C₅₀H₇₁N₁₃O₁₂

Products

Katalogové čísloBalení ks/bal.
05-23-0101-1MG Plastová ampulka 1 mg
Přidat k oblíbeným položkám
05-23-0101-25MG Skleněná láhev 25 mg
Přidat k oblíbeným položkám
05-23-0101-5MG Plastová ampulka 5 mg
Přidat k oblíbeným položkám
Description
OverviewPlays an important role in the regulation of blood pressure. Stimulates the release of aldosterone from the adrenal gland. Inhibits adenylate cyclase activity in spontaneously hypertensive rats. Has strong vasoconstrictive effects. Increases the entry of Ca2+ in heart muscle via voltage-sensitive channels and activates myosin light chain kinase. Also elicits an increase in voltage-dependent delayed rectifier K+ current in neurons. Activates JAK2 in smooth muscle cells. Activates p125FAK and a cytosolic 115-120 kDa calcium-dependent tyrosine kinase in rat epithelial cells. Also activates p60c-src as well as ERK1/2, JNK, and p38 MAP Kinase in vascular smooth muscle cells.
Catalogue Number05-23-0101
Brand Family Calbiochem®
SynonymsDRVYIHPF
References
ReferencesZhu, M., et al. 2000. J. Neurophysiol. 84, 2494.
Natarajan, R., et al. 1999. Hypertension 33, 378.
Mazzolai, L., et al. 1998. Hypertension 31, 1324.
Earp, H.S., et al. 1995. J. Biol. Chem. 270, 28440.
Ishida, M., et al. 1995. Circ. Res. 77, 1053.
Vyas, S.J., and Jackson, E.K. 1995. J. Pharmacol. Exp. Ther. 273, 768.
Product Information
CAS number4474-91-3
ATP CompetitiveN
FormWhite to off-white solid
Hill FormulaC₅₀H₇₁N₁₃O₁₂
Chemical formulaC₅₀H₇₁N₁₃O₁₂
Hygroscopic Hygroscopic
ReversibleN
Sold on the basis of peptide contentY
Quality LevelMQ100
Biological Information
Primary Targetadenylate cyclase activity
Purity≥98% by HPLC
Physicochemical Information
Cell permeableN
Peptide ContentY
Peptide SequenceH-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-OH
Safety Information according to GHS
RTECSBW2165000
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 week at 4°C or for up to 1 month at -20°C.
Global Trade Item Number
Katalogové číslo GTIN
05-23-0101-1MG 04055977206906
05-23-0101-25MG 04055977206913
05-23-0101-5MG 04055977206920