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565753 β-Secretase Substrate I, Fluorogenic

β-Secretase Substrate I, Fluorogenic MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: MCA-EVKMDAEFK(DNP)-NH₂

565753
  
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Replacement Information
Description
Overview

This product has been discontinued.





A specific fluorescent resonance energy transfer (FRET) substrate for the detection of β-secretase. Cleavage occurs between the Met-Asp residues.
Catalogue Number565753
Brand Family Calbiochem®
SynonymsMCA-EVKMDAEFK(DNP)-NH₂
References
ReferencesFarzan, M., et al. 2000. Proc. Natl. Acad. Sci. USA 97, 9712.
Kowalewski, T. and Holtzman, D.M. 1999. Proc. Natl. Acad. Sci. USA 96, 3686.
Ladror, U.S., et al. 1994. J. Protein Chem. 13, 357.
Product Information
FormLiquid
FormulationIn DMSO.
Hill FormulaC₆₆H₈₈N₁₄O₂₃S
Chemical formulaC₆₆H₈₈N₁₄O₂₃S
Applications
Biological Information
Purity≥95% by HPLC
Concentration Label Please refer to vial label for lot-specific concentration
Physicochemical Information
Emission max.
Excitation max.
Peptide SequenceMCA-Glu-Val-Lys-Met-Asp-Ala-Glu-Phe-Lys(DNP)-NH₂
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Protect from Moisture Protect from moisture
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
565753 0

Documentation

β-Secretase Substrate I, Fluorogenic Certificates of Analysis

TitleLot Number
565753

References

Přehled odkazů
Farzan, M., et al. 2000. Proc. Natl. Acad. Sci. USA 97, 9712.
Kowalewski, T. and Holtzman, D.M. 1999. Proc. Natl. Acad. Sci. USA 96, 3686.
Ladror, U.S., et al. 1994. J. Protein Chem. 13, 357.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision08-December-2008 JSW
SynonymsMCA-EVKMDAEFK(DNP)-NH₂
DescriptionA specific fluorescent resonance energy transfer (FRET) substrate for the detection of β-secretase activity. Cleavage occurs between methionine and aspartic acid residues. Excitation max: ~325 nm; emission max: ~393 nm
FormLiquid
FormulationIn DMSO.
Concentration Label Please refer to vial label for lot-specific concentration
Chemical formulaC₆₆H₈₈N₁₄O₂₃S
Peptide SequenceMCA-Glu-Val-Lys-Met-Asp-Ala-Glu-Phe-Lys(DNP)-NH₂
Purity≥95% by HPLC
Storage Protect from moisture
Protect from light
-20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
Toxicity Standard Handling
ReferencesFarzan, M., et al. 2000. Proc. Natl. Acad. Sci. USA 97, 9712.
Kowalewski, T. and Holtzman, D.M. 1999. Proc. Natl. Acad. Sci. USA 96, 3686.
Ladror, U.S., et al. 1994. J. Protein Chem. 13, 357.