Viresolve Prefilter Pod Disposable Devices

Description

The Viresolve^® Prefilter removes protein aggregates and improves the robustness of virus filtration operations. Implementing the Viresolve^® Prefilter improves the capacity of the Viresolve® Pro Device, results in more consistent filtration performance, and improves overall process economics.

Enhanced Viral Clearance

Viresolve NFP filters clear parvovirus from recombinant feed streams without compromising flow rates, adding speed and dependability to viral clearance in therapeutic drug manufacturing applications. These reliable filters are ideal for monoclonal antibody polishing applications eliminating small virus contaminants.

Improves NFP capacity reducing overall filtration costs

• Maintain high product yields
  
• Simple, predictable scale-up and scale-down

Increased Capacity and Filter Life

Utilizing this prefilter in series with Viresolve NFP filters (NFP) will allow you to take advantage of NFP’s high flow rates and product yield. The prefilter effectively removes fouling components of the feed, leading to dramatic increases in the performance of the Viresolve NFP filter. This improved capacity significantly reduces the cost of the viral clearance step.

Regulatory Compliance

Viresolve^® Prefilters are designed, developed, and manufactured in accordance with good manufacturing practices under an ISO^® 9001 Quality Management System.
Pods are integrity tested during manufacturing and supported by a Validation Guide to assist in compliance with regulatory requirements. For traceability and easy identification, each filter is labeled with the product name and identifying characteristics. Every filter is supported by a Certificate of Quality.

Multiple Formats Available

Viresolve^® Prefilters are offered in multiple device configurations.

• OptiScale™ 40 small scale disposable capsule filters
  
• Pod disposable devices (0.1 m², 0.5 m² and 1 m² filtration areas).

Pod devices are offered with an expandable holder system: the pilot scale holder can accommodate up to five 1 m² Pods, while the process scale holder expands to mount from 5 to 30 Pod devices. With the compact, modular design, you can increase productivity, shorten cycle-time and reduce costs.

Pod Disposable Devices

Scalable from pilot to process applications, this new innovative NFF device format offers process flexibility and linear scale-up.

Flexible Configurations
This patented technology consists of three Pod sizes and an expandable holder system.
Pod Prefilters are offered in 0.1 m², 0.5 m² and 1 m² filtration areas.
Two basic holders are available; the pilot scale holder is configurable with extension rods that can accommodate up to five 1 m² Pods, while the process scale holder expands to mount from 5 to 30 Pod devices. The stainless steel holder is not wetted by product and the connectors are disposable plastic. With the compact, modular design of Millipore’s new Pod system, you can increase productivity, shorten cycle-time and reduce costs.