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475989 MTT - CAS 298-93-1 - Calbiochem

Descripción

Replacement Information

Tabla espec. clave

CAS #Empirical Formula
298-93-1C₁₈H₁₆BrN₅S

Precios y disponibilidad

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      475989-1GM
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      Debe confirmarse disponibilidad
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          Description
          OverviewMembrane-permeable yellow dye that is reduced by mitochondrial reductases in living cells to form the dark blue product, MTT-formazan. Spectrophotometric measurement of MTT-formazan at 540 or 570 nm allows quantitation of cell viability. Used as a direct indicator of cytotoxicity (such as for screening cancer drugs) and apoptosis. An electron acceptor used for studying NADP-dependent dehydrogenases.
          Catalogue Number475989
          Brand Family Calbiochem®
          Synonyms3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium Bromide, Thiazole Blue
          References
          ReferencesLiu, Y., et al. 1997. J. Neurochem. 69, 581.
          Abdallah, M.A. 1980. Eur. J. Biochem. 112, 331.
          Product Information
          CAS number298-93-1
          ATP CompetitiveN
          FormYellow powder
          Hill FormulaC₁₈H₁₆BrN₅S
          Chemical formulaC₁₈H₁₆BrN₅S
          ReversibleN
          Structure formula ImageStructure formula Image
          Quality LevelMQ100
          Applications
          Biological Information
          Primary TargetUsed as a direct indicator of cytotoxicity and apoptosis.
          Purity≥98% by HPLC
          Physicochemical Information
          Cell permeableY
          ContaminantsSulfated ash: ≤0.5%; heavy metals: ≤0.001%
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          RTECSXF8060000
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Harmful & Carcinogenic / Teratogenic
          Storage +15°C to +30°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C.). Stock solutions are stable for up to 1 month at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications
          Global Trade Item Number
          Número de referencia GTIN
          475989-10GM 04061838430403
          475989-1GM 07790788050603

          Documentation

          MTT - CAS 298-93-1 - Calbiochem Ficha datos de seguridad (MSDS)

          Título

          Ficha técnica de seguridad del material (MSDS) 

          MTT - CAS 298-93-1 - Calbiochem Certificados de análisis

          CargoNúmero de lote
          475989

          Referencias bibliográficas

          Visión general referencias
          Liu, Y., et al. 1997. J. Neurochem. 69, 581.
          Abdallah, M.A. 1980. Eur. J. Biochem. 112, 331.
          Ficha técnica

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision06-December-2019 JSW
          Synonyms3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium Bromide, Thiazole Blue
          DescriptionMembrane-permeable yellow dye that is reduced by mitochondrial reductases in living cells to form the dark blue product, MTT-formazan. Spectrophotometric measurement of MTT-formazan at 540 or 570 nm allows quantitation of cell viability. Used as a direct indicator of cytotoxicity (such as for screening cancer drugs) and apoptosis. An electron acceptor used for studying NADP-dependent dehydrogenases.
          FormYellow powder
          CAS number298-93-1
          RTECSXF8060000
          Chemical formulaC₁₈H₁₆BrN₅S
          Structure formulaStructure formula
          Purity≥98% by HPLC
          ContaminantsSulfated ash: ≤0.5%; heavy metals: ≤0.001%
          SolubilityH₂O (5 mg/ml)
          Storage +15°C to +30°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C.). Stock solutions are stable for up to 1 month at -20°C.
          Toxicity Harmful & Carcinogenic / Teratogenic
          ReferencesLiu, Y., et al. 1997. J. Neurochem. 69, 581.
          Abdallah, M.A. 1980. Eur. J. Biochem. 112, 331.