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524950 SAFCVitamin B₁₂ (cyanocobalamin)

EMPROVE® ESSENTIAL Ph Eur,BP,USP

Vitamin B₁₂ (cyanocobalamin) MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Material Qualification Dossier
Quality Management Dossier (Open Access)
Operational Excellence Dossier
SDS
CoA
Certificates

Synonyms: Cyanocobalamin

CAS #: 68-19-9 EC Number: 200-680-0 Molar Mass: 1355.37 g/mol Hill Formula: C₆₃H₈₈Co N₁₄O₁₄P Grade: Ph Eur,BP,USP

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Overview

Replacement Information

Key Spec Table

CAS #	EC Number	Hill Formula	Molar Mass	Grade Value
68-19-9	200-680-0	C₆₃H₈₈Co N₁₄O₁₄P	1355.37 g/mol	Ph Eur,BP,USP

Pricing & Availability

Catalogue Number	Availability	Packaging	Qty/Pack	Price	Quantity
5249500010	Retrieving availability... — Limited Availability In Stock Discontinued Limited Quantities Available Availability to be confirmed Login to See Inventory In Stock Limited Availability In Stock Remaining : Will advise Remaining : Will advise Will advise Contact Customer Service Contact Customer Service Contact Customer Service Contact Customer Service	Glass bottle	10 g	Retrieving price... Price could not be retrieved Minimum Quantity is a multiple of Maximum Quantity is Upon Order Completion More Information You Saved () — Request Pricing Login to See Your Pricing	Check Availability —	Add To Favorites Add To Favorites Added To My Favorites
5249500100	Retrieving availability... — Limited Availability In Stock Discontinued Limited Quantities Available Availability to be confirmed Login to See Inventory In Stock Limited Availability In Stock Remaining : Will advise Remaining : Will advise Will advise Contact Customer Service Contact Customer Service Contact Customer Service Contact Customer Service	Metal can	100 g	Retrieving price... Price could not be retrieved Minimum Quantity is a multiple of Maximum Quantity is Upon Order Completion More Information You Saved () — Request Pricing Login to See Your Pricing	Check Availability —	Add To Favorites Add To Favorites Added To My Favorites
5249500250	Retrieving availability... — Limited Availability In Stock Discontinued Limited Quantities Available Availability to be confirmed Login to See Inventory In Stock Limited Availability In Stock Remaining : Will advise Remaining : Will advise Will advise Contact Customer Service Contact Customer Service Contact Customer Service Contact Customer Service	Plastic bottle	250 g	Retrieving price... Price could not be retrieved Minimum Quantity is a multiple of Maximum Quantity is Upon Order Completion More Information You Saved () — Request Pricing Login to See Your Pricing	Check Availability —	Add To Favorites Add To Favorites Added To My Favorites
CO1E5249500250	Retrieving availability... — Limited Availability In Stock Discontinued Limited Quantities Available Availability to be confirmed Login to See Inventory In Stock Limited Availability In Stock Remaining : Will advise Remaining : Will advise Will advise Contact Customer Service Contact Customer Service Contact Customer Service Contact Customer Service		250 g	Retrieving price... Price could not be retrieved Minimum Quantity is a multiple of Maximum Quantity is Upon Order Completion More Information You Saved () — Request Pricing Login to See Your Pricing	Check Availability —	Add To Favorites Add To Favorites Added To My Favorites
CO1H5249500250	Retrieving availability... — Limited Availability In Stock Discontinued Limited Quantities Available Availability to be confirmed Login to See Inventory In Stock Limited Availability In Stock Remaining : Will advise Remaining : Will advise Will advise Contact Customer Service Contact Customer Service Contact Customer Service Contact Customer Service		250 g	Retrieving price... Price could not be retrieved Minimum Quantity is a multiple of Maximum Quantity is Upon Order Completion More Information You Saved () — Request Pricing Login to See Your Pricing	Check Availability —	Add To Favorites Add To Favorites Added To My Favorites

Description
Catalogue Number	524950
Synonyms	Cyanocobalamin

References

Product Information
CAS number	68-19-9
EC number	200-680-0
Grade	Ph Eur,BP,USP
Hill Formula	C₆₃H₈₈Co N₁₄O₁₄P
Molar Mass	1355.37 g/mol
HS Code	2936 26 10
Structure formula Image
Quality Level	MQ500

Applications

Biological Information

Physicochemical Information
Melting Point	>300 °C
pH value	6 (H₂O)
Bulk density	450 - 600 kg/m3
Solubility	12 g/l

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS
RTECS	GG3750000
Storage class	10 - 13 Other liquids and solids
WGK	WGK 1 slightly hazardous to water

Safety Information

Product Usage Statements

Storage and Shipping Information
Storage	Store at +15°C to +25°C.

Packaging Information

Transport Information
Declaration (railroad and road) ADR, RID	Kein Gefahrgut
Declaration (transport by air) IATA-DGR	No Dangerous Good
Declaration (transport by sea) IMDG-Code	No Dangerous Good

Supplemental Information

Specifications
Assay (photometric, calculated on dried substance)	96.0 - 102.0 %
Identity (Cobalt)	passes test
Identity (HPLC)	passes test
Appearance	dark-red, crystalline powder or dark-red crystals
Absorption ratio (A 361 nm/278 nm)	1.70 - 1.90
Absorption ratio (A 361 nm/550 nm)	3.15 - 3.40
Al (Aluminium)	≤ 1 ppm
Fe (Iron)	≤ 130 ppm
Mn (Manganese)	≤ 25 ppm
Zn (Zinc)	≤ 25 ppm
Related substances (HPLC, Ph Eur) (Impurity A)	≤ 0.7 %
Related substances (HPLC, Ph Eur) (Impurity B)	≤ 0.5 %
Related substances (HPLC, Ph Eur) (Impurity C)	≤ 1.5 %
Related substances (HPLC, Ph Eur) (Impurity D)	≤ 0.5 %
Related substances (HPLC, Ph Eur) (Impurity E)	≤ 0.5 %
Related substances (HPLC, Ph Eur) (Impurity F)	≤ 0.5 %
Related substances (HPLC, Ph Eur) (Each unspecified impurity)	≤ 0.2 %
Related substances (HPLC, Ph Eur) (Sum of all impurities)	≤ 3.0 %
Related substances (HPLC, USP, 7ß,8ß-Lactocyanocobalamin)	≤ 1.0 %
Related substances (HPLC, USP, 50-Carboxycyanocobalamin)	≤ 0.5 %
Related substances (HPLC, USP, 32-Carboxycyanocobalamin)	≤ 2.0 %
Related substances (HPLC, USP, 34-Methylcyanocobalamin)	≤ 1.0 %
Related substances (HPLC, USP, 8-Epi-cyanocobalamin)	≤ 1.0 %
Related substances (HPLC, USP, Any other unidentified impurity)	≤ 0.5 %
Related substances (HPLC, USP, Total impurities)	≤ 3.0 %
Acetone (HS-GC)	≤ 5000 ppm
Other residual solvents (ICH Q3C)	excluded by production process
Loss on Drying (105 °C)	≤ 12.0 %
Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
Corresponds to Ph Eur, BP, USP
	≤ 12.0 %
Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
Corresponds to Ph Eur, BP, USP
Corresponds to Ph Eur, BP, USP

Global Trade Item Number
Catalogue Number	GTIN
5249500010	04022536261874
5249500100	04022536261881
5249500250	04022536261898
CO1E5249500250	0
CO1H5249500250	0

Documentation

Material Qualification Dossier

Title	Version
Material Qualification Dossier	10.0

Quality Management Dossier (Open Access)

Title
Quality Management Dossier

Operational Excellence Dossier

Title
Operational Excellence Dossier

Vitamin B₁₂ (cyanocobalamin) SDS

Title
Safety Data Sheet (SDS)

Vitamin B₁₂ (cyanocobalamin) Certificates of Analysis

Product Number	Packaging	Specification	Lot Number
5249500010	Glass bottle	PDF Specification Document	Enter Lot Number
5249500100	Metal can	PDF Specification Document	Enter Lot Number
5249500250	Plastic bottle	PDF Specification Document	Enter Lot Number
CO1E5249500250		PDF Specification Document	Enter Lot Number
CO1H5249500250		PDF Specification Document	Enter Lot Number

Certificates

Title
Aflatoxin Certificate for 524950 Vitamin B12 (cyanocobalamin) EMPROVE® ESSENTIAL Ph Eur,BP,USP
BSE/TSE Certificate for 524950 Vitamin B12 (cyanocobalamin) EMPROVE® ESSENTIAL Ph Eur,BP,USP
GMO Certificate for 524950 Vitamin B12 (cyanocobalamin) EMPROVE® ESSENTIAL Ph Eur,BP,USP
Halal Certificate for 524950 Vitamin B12 (cyanocobalamin) EMPROVE® ESSENTIAL Ph Eur,BP,USP
Kosher Certificate for 524950 Vitamin B12 (cyanocobalamin) EMPROVE® ESSENTIAL Ph Eur,BP,USP

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524950 SAFCVitamin B₁₂ (cyanocobalamin)

EMPROVE® ESSENTIAL Ph Eur,BP,USP

Synonyms: Cyanocobalamin

Recommended Products

Overview

Key Spec Table

Pricing & Availability

Documentation

Material Qualification Dossier

Quality Management Dossier (Open Access)

Operational Excellence Dossier

Vitamin B₁₂ (cyanocobalamin) SDS

Vitamin B₁₂ (cyanocobalamin) Certificates of Analysis

Certificates

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