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108386 Tris(hydroxymethyl)aminomethane

(Trometamol) EMPROVE® EXPERT Ph Eur,BP,ChP,JPC,USP

Tris(hydroxymethyl)aminomethane MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Trometamol, Aminomethylidine trimethanol, 2-Amino-2-hydroxymethyl-1.3-propanediol, TRIS-buffer

CAS #: 77-86-1 EC Number: 201-064-4 Molar Mass: 121.14 g/mol Chemical Formula: H₂NC(CH₂OH)₃ Hill Formula: C₄H₁₁NO₃ Grade: Ph Eur,BP,ChP,JPC,USP
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108386
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Key Spec Table

CAS #EC NumberHill FormulaChemical FormulaMolar MassGrade Value
77-86-1201-064-4C₄H₁₁NO₃H₂NC(CH₂OH)₃121.14 g/molPh Eur,BP,ChP,JPC,USP

Pricing & Availability

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1083861000
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      1083865000
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          1083869025
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              CO1E1083861000
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                  CO1E1083869025
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                      Description
                      Catalogue Number108386
                      SynonymsTrometamol, Aminomethylidine trimethanol, 2-Amino-2-hydroxymethyl-1.3-propanediol, TRIS-buffer
                      DescriptionTris(hydroxymethyl)aminomethane
                      References
                      Product Information
                      CAS number77-86-1
                      EC number201-064-4
                      GradePh Eur,BP,ChP,JPC,USP
                      Hill FormulaC₄H₁₁NO₃
                      Chemical formulaH₂NC(CH₂OH)₃
                      Molar Mass121.14 g/mol
                      HS Code2922 19 99
                      Structure formula ImageStructure formula Image
                      Quality LevelMQ500
                      Applications
                      Biological Information
                      Physicochemical Information
                      Boiling point219 - 220 °C (13.3 hPa)
                      Density1.32 g/cm3 (20 °C)
                      Melting Point169 °C
                      pH value10.2 - 10.6 (6 g/l, H₂O, 20 °C)
                      Vapor pressure<0.1 hPa (20 °C)
                      Bulk density840 kg/m3
                      Solubility678 g/l
                      Dimensions
                      Materials Information
                      Toxicological Information
                      LD 50 oralLD50 Rat > 5000 mg/kg
                      LD 50 dermalLD50 Rat > 5000 mg/kg
                      Safety Information according to GHS
                      RTECSTY2900000
                      Storage class10 - 13 Other liquids and solids
                      WGKWGK 1 slightly hazardous to water
                      Disposal3
                      Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
                      Safety Information
                      Product Usage Statements
                      Storage and Shipping Information
                      StorageNoTempLimit
                      Packaging Information
                      Transport Information
                      Supplemental Information
                      Specifications
                      Global Trade Item Number
                      Catalogue Number GTIN
                      1083861000 04022536103846
                      1083865000 04022536775487
                      1083869025 04022536103853
                      CO1E1083861000 04061839010260
                      CO1E1083869025 0

                      Documentation

                      Material Qualification Dossier

                      TitleVersion
                      6.0

                      Quality Management Dossier (Open Access)

                      Title

                      Operational Excellence Dossier

                      Title

                      Tris(hydroxymethyl)aminomethane SDS

                      Title

                      Safety Data Sheet (SDS) 

                      Tris(hydroxymethyl)aminomethane Certificates of Analysis

                      Product Number PackagingSpecificationLot Number
                      1083861000 Plastic bottlePDF Specification Document
                      1083865000 Plastic bottlePDF Specification Document
                      1083869025 PDF Specification Document
                      CO1E1083861000 PDF Specification Document
                      CO1E1083869025 PDF Specification Document

                      Certificates

                      Title

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                      Categories

                      Biopharmaceutical Manufacturing > Downstream Processing > Chromatography > Process Chemicals > Buffers
                      Small Molecule Pharmaceuticals > Formulation > Semisolid Dosage Form > Acidulants and pH Adjustments
                      Biopharmaceutical Manufacturing > Formulation > Liquid Dosage > pH Adjustments and Isotonizers
                      Small Molecule Pharmaceuticals > Formulation > Liquid Dosage Form > pH Adjustments and Isotonizers