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625625 Trehalose, Dihydrate - CAS 6138-23-4 - Calbiochem

Non-reducing disaccharide which yields 2 moles of D-glucose upon acid hydrolysis. Inhibits polyglutamine-mediated protein aggregation both in vivo and in vitro.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 1-O-α-D-Glucopyranosyl-α-D-glucopyranoside

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625625
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Overview

Key Spec Table

CAS #Empirical Formula
6138-23-4C₁₂H₂₂O₁₁ · 2H₂O

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      625625-50GM
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          Description
          OverviewNon-reducing disaccharide which yields 2 moles of D-glucose upon acid hydrolysis. Inhibits polyglutamine-mediated protein aggregation both in vivo and in vitro. Oral administration of trehalose has been shown to effectively extend lifespan in a murine Huntington disease model. Also known to accumulate in osmotically-stressed cultured bacterial cells and protect against the adverse effects of dehydration.
          Catalogue Number625625
          Brand Family Calbiochem®
          Synonyms1-O-α-D-Glucopyranosyl-α-D-glucopyranoside
          References
          ReferencesSarkar, S., et al. 2007. J. Biol. Chem. In press.
          Tanaka, M., et al. 2004. Nat. Med. 10, 148.
          Sastry, G.M. and Agmon, N. 1997. Biochemistry 36, 7097.
          Product Information
          CAS number6138-23-4
          FormSolid
          Hill FormulaC₁₂H₂₂O₁₁ · 2H₂O
          Chemical formulaC₁₂H₂₂O₁₁ · 2H₂O
          Structure formula ImageStructure formula Image
          Quality LevelMQ100
          Biological Information
          Purity≥97.5% by Assay
          Physicochemical Information
          ContaminantsHeavy metals: <10 ppm; iron: <5 ppm
          Safety Information
          S PhraseS: 24/25-37-45

          Avoid contact with skin and eyes.
          Wear suitable gloves.
          In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage +15°C to +30°C
          Do not freeze Ok to freeze
          Global Trade Item Number
          Catalogue Number GTIN
          625625-1KG 04055977262728
          625625-50GM 07790788051976