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19-143 PD 98059

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19-143
5 mg  
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      Overview

      Replacement Information

      Key Spec Table

      Uni Prot Number
      7DHTW9
      Description
      Catalogue Number19-143
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionPD 98059
      References
      Product Information
      HS Code3822 19 90
      PresentationC16H13NO3
      Quality LevelMQ100
      Applications
      Key Applications
      • Kinase Assay
      Application NotesPotent, selective and cell-permeable inhibitor of MAPK kinase, MAPK/ERK, or MEKK.
      Biological Information
      UniProt Number
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditions2 years at -20°C
      Packaging Information
      Material Size5 mg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      19-143 04053252590498

      Documentation

      PD 98059 SDS

      Title

      Safety Data Sheet (SDS) 

      PD 98059 Certificates of Analysis

      TitleLot Number
      PD 98059 3082825
      PD 98059 2975408
      PD 98059 2955861
      PD 98059 2886369
      PD 98059 - 19199 19199
      PD 98059 - 20674 20674
      PD 98059 - 22807 22807
      PD 98059 - 2562481 2562481
      PD 98059 - 27988 27988
      PD 98059 - 3185056 3185056

      References

      Reference overviewApplicationPub Med ID
      Pitx2a expression alters actin-myosin cytoskeleton and migration of HeLa cells through Rho GTPase signaling.
      Wei, Qize and Adelstein, Robert S
      Mol. Biol. Cell, 13: 683-97 (2002)  2002

      Show Abstract
      Activation Assay11854422 11854422
      PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo.
      Alessi, D R, et al.
      J. Biol. Chem., 270: 27489-94 (1995)  1995

      Show Abstract
      7499206 7499206
      A synthetic inhibitor of the mitogen-activated protein kinase cascade.
      Dudley, D T, et al.
      Proc. Natl. Acad. Sci. U.S.A., 92: 7686-9 (1995)  1995

      Show Abstract
      7644477 7644477
      Inhibition of MAP kinase kinase blocks the differentiation of PC-12 cells induced by nerve growth factor.
      Pang, L, et al.
      J. Biol. Chem., 270: 13585-8 (1995)  1995

      Show Abstract
      7775407 7775407

      Related Products & Applications

      Product Families

      Categories

      Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Protein Phosphorylation / Dephosphorylation > MAP Kinase Inhibitors