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106757 Methyl 4-hydroxybenzoate

EMPROVE® EXPERT Ph Eur,BP,ChP,JP,NF

Methyl 4-hydroxybenzoate MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Methylparaben, 4-Hydroxybenzoic acid methyl ester

CAS #: 99-76-3 EC Number: 202-785-7 Molar Mass: 152.15 g/mol Chemical Formula: 4-(OH)C₆H₄(COOCH₃) Hill Formula: C₈H₈O₃ Grade: Ph Eur,BP,ChP,JP,NF
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106757
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Key Spec Table

CAS #EC NumberHill FormulaChemical FormulaMolar MassGrade Value
99-76-3202-785-7C₈H₈O₃4-(OH)C₆H₄(COOCH₃)152.15 g/molPh Eur,BP,ChP,JP,NF

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                  Description
                  Catalogue Number106757
                  SynonymsMethylparaben, 4-Hydroxybenzoic acid methyl ester
                  DescriptionMethyl 4-hydroxybenzoate
                  References
                  Product Information
                  CAS number99-76-3
                  EC number202-785-7
                  GradePh Eur,BP,ChP,JP,NF
                  Hill FormulaC₈H₈O₃
                  Chemical formula4-(OH)C₆H₄(COOCH₃)
                  Molar Mass152.15 g/mol
                  HS Code2918 29 22
                  Structure formula ImageStructure formula Image
                  Quality LevelMQ500
                  Applications
                  Biological Information
                  Physicochemical Information
                  Density1.38 g/cm3 (20 °C)
                  Flash point168 °C Not applicable
                  Ignition temperature>600 °C
                  Melting Point125 °C
                  pH value5.72 (1.88 g/l, H₂O, 20 °C) (saturated solution)
                  Vapor pressure<1 hPa (20 °C)
                  Bulk density300 - 400 kg/m3
                  Solubility1.88 g/l
                  Dimensions
                  Materials Information
                  Toxicological Information
                  LD 50 oralLD50 Rat 2100 mg/kg
                  Safety Information according to GHS
                  Hazard Pictogram(s) Hazard Pictogram(s)
                  Hazard Statement(s)H411: Toxic to aquatic life with long lasting effects.
                  Precautionary Statement(s)P273: Avoid release to the environment.
                  P391: Collect spillage.
                  P501: Dispose of contents/ container to an approved waste disposal plant.
                  RTECSDH2450000
                  Storage class10 - 13 Other liquids and solids
                  WGKWGK 1 slightly hazardous to water
                  Disposal3
                  Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
                  Safety Information
                  Product Usage Statements
                  Storage and Shipping Information
                  StorageStore at +15°C to +25°C.
                  Packaging Information
                  Transport Information
                  Declaration (railroad and road) ADR, RIDUN 3077 , 9, III
                  Declaration (transport by air) IATA-DGRUN 3077 , 9, III
                  Declaration (transport by sea) IMDG-CodeUN 3077 , 9, III, Marine Pollutant: P
                  Supplemental Information
                  Specifications
                  Assay (HPLC, Ph. Eur., BP, JP, NF)98.0 - 102.0 %
                  Assay (HPLC, calc. on dried substance) (ChP)98.0 - 102.0 %
                  Identity (IR-spectrum)passes test
                  Identity (melting range)passes test
                  Identity (HPLC) (ChP)passes test
                  Identity (UV-spectrum)passes test
                  Appearance of solution (100 g/l, Ethanol 96 %)clear and not more intense in color than reference solution BY₆
                  Appearance of solution (100 g/l, ethanol 96 %) (ChP)clear (≤ 1.5 NTU) and not more intense in color than reference solution Y₁ or YG₁
                  Aciditypasses test
                  Melting range (lower value)≥ 125 °C
                  Melting range (upper value)≤ 128 °C
                  Chloride (Cl)≤ 350 ppm
                  Sulfate (SO₄)≤ 240 ppm
                  As (Arsenic)≤ 1 ppm
                  Heavy metals (as Pb)≤ 10 ppm
                  Related substances (HPLC, Ph. Eur., BP, ChP, JP, NF)passes test
                  p-Hydroxy benzoic acid≤ 0.3 %
                  Largest unspecified impurity≤ 0.4 %
                  Sum of all impurities≤ 0.8 %
                  Methanol (HS-GC)≤ 3000 ppm
                  Other residual solvents (ICH Q3C)excluded by manufactoring process
                  Sulfated ash (600 °C)≤ 0.1 %
                  Residue on ignition (500 °C)≤ 0.1 %
                  Loss on drying (room temperature, vacuum)≤ 0.5 %
                  Total aerobic microbial count (TAMC)≤ 10²
                  Total combined yeasts/moulds count (TYMC)≤ 10²
                  Endotoxins≤ 200 I.U./g
                  Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
                  Not for food use.
                  Corresponds to Ph Eur, BP, ChP, JP, NF.
                  Global Trade Item Number
                  Catalogue Number GTIN
                  1067575000 04022536081847
                  1067579024 04022536938677
                  CO1E1067575000-1 04061839010178
                  CO1E1067579024 04061839010185

                  Documentation

                  Material Qualification Dossier

                  TitleVersion
                  8.0

                  Quality Management Dossier (Open Access)

                  Title

                  Operational Excellence Dossier

                  Title

                  Methyl 4-hydroxybenzoate SDS

                  Title

                  Safety Data Sheet (SDS) 

                  Methyl 4-hydroxybenzoate Certificates of Analysis

                  Product Number PackagingSpecificationLot Number
                  1067575000 Fibre cartonPDF Specification Document
                  1067579024 Double PE SackPDF Specification Document
                  CO1E1067575000-1 PDF Specification Document
                  CO1E1067579024 PDF Specification Document

                  Certificates

                  Title