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HCCBP3MAG-58K MILLIPLEX MAP Human Circulating Cancer Biomarker Magnetic Bead Panel 3 - Cancer Multiplex Assay

Circulating Cancer Biomarker Bead-Based Multiplex Assays using the Luminex technology enables the simultaneous analysis of multiple oncology biomarkers in various tumor types in human serum, plasma and cell culture samples.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Key Applications: Multiplexing Detection Methods: Luminex xMAP Research Category: Cancer
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HCCBP3MAG-58K
Design And Price Your Kit

Overview

Replacement Information

Key Spec Table

Analytes AvailableSpecies ReactivityKey ApplicationsDetection Methods
Cathepsin D Galectin-3 Ferritin Fibroblast Activation Protein IGFBP-3 Melanoma Inhibitory Activation Protein Myeloperoxidase Sex Hormone Binding Globulin HMplexLuminex xMAP
Description
Catalogue NumberHCCBP3MAG-58K
Trade Name
  • MILLIPLEX
DescriptionMILLIPLEX MAP Human Circulating Cancer Biomarker Magnetic Bead Panel 3 - Cancer Multiplex Assay
OverviewMILLIPLEX MAP Circulating Cancer Biomarker Magnetic Bead Panel 3 consists of 8 circulating cancer biomarkers that can be used to study a wide range of tumor types.
Background InformationCancer research has always focused on intracellular biomarkers, such as HER2 and B-Raf, and in recent years, more and more attention has shifted to include extracellular cancer biomarkers. While the use of intracellular markers in research helps clarify the process of oncogenesis, circulating cancer biomarkers give insight into how the body responds to the presence of a tumor, the dysregulation of homeostasis and the relationship between a tumor and its environment. Study of isolated biomarkers, whether intracellular or circulating, is often inadequate to fully characterize the complex relationship between tumor and non-tumor. Consequently, multianalyte panels have become essential tools that enable researchers to measure cancer biomarkers simultaneously, teasing out these relationships and applying them to understand tumor biology.
References
Product Information
Detection methodLuminex xMAP
ConfigurationDesign your multiplex kit by choosing available analytes within this panel.
Precision, %
  • Intra Assay: 5 - 8
  • Inter Assay: 5 - 17
Panel TypeMAGNETIC Circulating Cancer
Quality LevelMQ200
Applications
ApplicationCirculating Cancer Biomarker Bead-Based Multiplex Assays using the Luminex technology enables the simultaneous analysis of multiple oncology biomarkers in various tumor types in human serum, plasma and cell culture samples.
Key Applications
  • Multiplexing
Application Notes• This is an overnight incubation assay requiring 25 µL of 1:50 dilution plasma or serum, or 25 μL of diluted tissue/cell lysate or culture supernatant per well (dilution factors may vary).
• This kit may be used for the analysis of all or any combination of the cancer biomarkers in serum, plasma or tissue/cell lysate and culture.
Biological Information
Species Reactivity
  • Human
Analytes Available
  • Cathepsin D
  • Galectin-3
  • Ferritin
  • Fibroblast Activation Protein
  • IGFBP-3
  • Melanoma Inhibitory Activation Protein
  • Myeloperoxidase
  • Sex Hormone Binding Globulin
Assay PanelEverything you need in a single kit.
Cross ReactivityCross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible.
Accuracy
  • 74% - 126%
Physicochemical Information
Sensitivity
  • Refer to kit protocol for sensitivities of individual biomarkers.
Standard Curve Range
  • 0.07 - 50 ng/mL: Fibroblast Activation Protein α
  • 0.27 - 200 ng/mL: Cathepsin D, IGFBP3
  • 0.03 - 25 ng/mL: Ferritin
  • 0.004 - 3 ng/mL: Galectin-3
  • 0.1 - 75 ng/mL: Melanoma Inhibitory Activity Protein
  • 0.02 - 20 ng/mL: Myeloperoxidase
  • 0.03 - 25 nM: Sex Hormone Binding Globulin*

    *SHBG Standard was calibrated against WHO standard 08/266 and 250 ng/mL standard was equivalent to 25 nM of WHO standard
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsRecommended storage for kit components is 2 - 8°C.
Packaging Information
Material Size96-well plate
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
HCCBP3MAG-58K 04053252988448

Documentation

Protocols

Title
Protocol- HCCBP3MAG-58K

MILLIPLEX MAP Human Circulating Cancer Biomarker Magnetic Bead Panel 3 - Cancer Multiplex Assay SDS

Title

Safety Data Sheet (SDS) 

Brochure

Title
The Power of Biomarker Analysis

Technical Info

Title
96 well Template 2 Up
96 well Template Single
HCCBP3MAG-58K xPonent Protocol Template Version Magpix
HCCBP3MAG-58K xPonent Protocol Template Version 3.1
Quality Control Range Sheet- HCC3-111 and HCC3-211
Quality Control Ranges: Human Circulating Cancer Biomarker Magnetic Bead Panel 3

Newsletters / Publications

Title
Article: Detection and localization of surgically resectable cancers with a multi-analyte blood test