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233156 Cleland’s Reagent, Molecular Biology Grade - CAS 3483-12-3 - Calbiochem

A protective agent for SH groups.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 1,4-Dithiothreitol, DTT

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233156
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
3483-12-3C₄H₁₀O₂S₂

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      Description
      OverviewA protective agent for SH groups.
      Catalogue Number233156
      Brand Family Calbiochem®
      Synonyms1,4-Dithiothreitol, DTT
      References
      Product Information
      CAS number3483-12-3
      FormWhite solid to powder
      Hill FormulaC₄H₁₀O₂S₂
      Chemical formulaC₄H₁₀O₂S₂
      Quality LevelMQ100
      Applications
      Biological Information
      Purity≥99% by titration
      Physicochemical Information
      ContaminantsDNases, proteases, RNases: none detected. Absorbance (100 mM, 1 cm, 260 nm): ≤0.500; (100 mM, 1 cm, 280 nm): ≤0.100
      Heavy metals≤0.001%
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSEK1610000
      Safety Information
      R PhraseR: 22-36/38

      Harmful if swallowed.
      Irritating to eyes and skin.
      S PhraseS: 26-36

      In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
      Wear suitable protective clothing.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Harmful
      Storage +2°C to +8°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      233156-10GM 04055977217759

      Documentation

      Cleland’s Reagent, Molecular Biology Grade - CAS 3483-12-3 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      Cleland’s Reagent, Molecular Biology Grade - CAS 3483-12-3 - Calbiochem Certificates of Analysis

      TitleLot Number
      233156
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision14-November-2017 JSW
      Synonyms1,4-Dithiothreitol, DTT
      DescriptionWater-soluble protective reagent for sulfhydryl groups [absorbance (100 mM): ≤0.5 at 260 nm; ≤0.1 at 280 nm]. It is capable of maintaining monothiols completely in the reduced state and of reducing disulfides quantitatively. Since it readily permeates cell membranes, it can protect protein sulfhydryls and restore enzyme activity lost by oxidation.
      FormWhite solid to powder
      Intert gas (Yes/No) Packaged under inert gas
      CAS number3483-12-3
      RTECSEK1610000
      Chemical formulaC₄H₁₀O₂S₂
      Purity≥99% by titration
      ContaminantsDNases, proteases, RNases: none detected. Absorbance (100 mM, 1 cm, 260 nm): ≤0.500; (100 mM, 1 cm, 280 nm): ≤0.100
      SolubilityH₂O (15 mg/ml)
      Storage +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Harmful
      Merck USA index14, 3376