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137003 Citric acid monohydrate

Overview

Replacement Information

Key Spec Table

CAS #EC NumberHill FormulaMolar MassGrade Value
5949-29-1201-069-1C₆H₈O₇ * H₂O210.14 g/molPh Eur,BP,ChP,JP,USP

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                                                                  Description
                                                                  Catalogue Number137003
                                                                  Synonyms2-Hydroxypropane-1,2,3-tricarboxylic acid, Hydroxytricarballylic acid
                                                                  References
                                                                  Product Information
                                                                  CAS number5949-29-1
                                                                  EC number201-069-1
                                                                  GradePh Eur,BP,ChP,JP,USP
                                                                  Hill FormulaC₆H₈O₇ * H₂O
                                                                  Molar Mass210.14 g/mol
                                                                  HS Code2918 14 00
                                                                  Structure formula ImageStructure formula Image
                                                                  Quality LevelMQ500
                                                                  Applications
                                                                  Biological Information
                                                                  Physicochemical Information
                                                                  Density1.54 g/cm3 (20 °C)
                                                                  Flash point173.9 °C Not applicable
                                                                  Melting Point135 - 152 °C
                                                                  pH value1.8 (50 g/l, H₂O, 20 °C)
                                                                  Vapor pressure<1 Pa (25 °C)
                                                                  Bulk density800 - 1000 kg/m3
                                                                  Solubility880 g/l
                                                                  Dimensions
                                                                  Materials Information
                                                                  Toxicological Information
                                                                  LD 50 oralLD50 Rat 3000 mg/kg
                                                                  Safety Information according to GHS
                                                                  Hazard Pictogram(s) Hazard Pictogram(s)
                                                                  Hazard Statement(s)H319: Causes serious eye irritation.
                                                                  H335: May cause respiratory irritation.
                                                                  Precautionary Statement(s)P261: Avoid breathing dust.
                                                                  P264: Wash skin thoroughly after handling.
                                                                  P271: Use only outdoors or in a well-ventilated area.
                                                                  P280: Wear eye protection/ face protection.
                                                                  P304 + P340 + P312: IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/doctor if you feel unwell.
                                                                  P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
                                                                  Signal WordWarning
                                                                  RTECSGE7810000
                                                                  Storage class10 - 13 Other liquids and solids
                                                                  WGKWGK 1 slightly hazardous to water
                                                                  Disposal3
                                                                  Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
                                                                  Safety Information
                                                                  Categories of dangerirritant
                                                                  Product Usage Statements
                                                                  Storage and Shipping Information
                                                                  StorageStore at +15°C to +25°C.
                                                                  Packaging Information
                                                                  Transport Information
                                                                  Declaration (railroad and road) ADR, RIDKein Gefahrgut
                                                                  Declaration (transport by air) IATA-DGRNo Dangerous Good
                                                                  Declaration (transport by sea) IMDG-CodeNo Dangerous Good
                                                                  Supplemental Information
                                                                  Specifications
                                                                  Assay (alkalimetric, calculated on anhydrous substance)99.5 - 100.5 %
                                                                  Identity (IR-spectrum)passes test
                                                                  Identity (wet chemistry)passes test
                                                                  Appearancewhite to almost white or colorless crystals
                                                                  Appearance of solution (200 g/l; water)clear (≤ 1.5 NTU) and not more intense in color than reference solution Y₇, BY₇ or GY₇
                                                                  Chloride (Cl)≤ 5 ppm
                                                                  Sulfate (SO₄)≤ 50 ppm
                                                                  Heavy metals (as Pb)≤ 5 ppm
                                                                  Al (Aluminium)≤ 0.2 ppm
                                                                  As (Arsenic)≤ 1 ppm
                                                                  Ca (Calcium)passes test
                                                                  Fe (Iron)≤ 10 ppm
                                                                  Oxalates (as C₂H₂O₄)≤ 360 ppm
                                                                  Oxalate (C₂H₂O₄) (ChP)passes test
                                                                  Residual solvents (ICH (Q3C))excluded by manufacturing process
                                                                  Readily carbonisable substancepasses test
                                                                  Sulfated ash (600 °C)≤ 0.05 %
                                                                  Water (according to Karl Fischer)7.5 - 9.0 %
                                                                  Total aerobic microbial count (TAMC)≤ 100 CFU/g
                                                                  Total combined yeasts/moulds count (TYMC)≤ 10 CFU/g
                                                                  Bile-tolerant gram-negative bacteria (absent in 1 g)passes test
                                                                  Candida albicans (absent in 1 g)passes test
                                                                  Escherichia coli (absent in 1 g)passes test
                                                                  Pseudomonas aeruginosa (absent in 1 g)passes test
                                                                  Salmonella (absent in 10 g)passes test
                                                                  Staphylococcus aureus (absent in 1 g)passes test
                                                                  DNases (Exo- and endonucleases)not detectable
                                                                  RNasesnot detectable
                                                                  Bacterial endotoxins< 10

                                                                  Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
                                                                  Corresponds to Ph. Eur., BP, ChP, JP, USP
                                                                  Global Trade Item Number
                                                                  Catalogue Number GTIN
                                                                  1370031000 04027269364946
                                                                  1370035000 04027269061432
                                                                  1370039012 04027269077426
                                                                  1370039029 04027269061968
                                                                  CO1E1370031000 0
                                                                  CO1E1370035000 0
                                                                  CO1E1370039012 0
                                                                  CO1E1370039029 0
                                                                  CO1H1370031000 0
                                                                  CO1H1370035000 0
                                                                  CO1H1370039012 0
                                                                  CO1H1370039029 0
                                                                  CO1I1370031000 0
                                                                  CO1I1370035000 0
                                                                  CO1I1370039012 0
                                                                  CO1I1370039029 0

                                                                  Documentation

                                                                  Material Qualification Dossier

                                                                  TitleVersion
                                                                  9.0

                                                                  Quality Management Dossier (Open Access)

                                                                  Title

                                                                  Operational Excellence Dossier

                                                                  Title

                                                                  Citric acid monohydrate SDS

                                                                  Title

                                                                  Safety Data Sheet (SDS) 

                                                                  Citric acid monohydrate Certificates of Analysis

                                                                  Product Number PackagingSpecificationLot Number
                                                                  1370031000 Plastic bottlePDF Specification Document
                                                                  1370035000 Plastic bottlePDF Specification Document
                                                                  1370039012 Bucket, plasticPDF Specification Document
                                                                  1370039029 Double PE SackPDF Specification Document
                                                                  CO1E1370031000 PDF Specification Document
                                                                  CO1E1370035000 PDF Specification Document
                                                                  CO1E1370039012 PDF Specification Document
                                                                  CO1E1370039029 PDF Specification Document
                                                                  CO1H1370031000 PDF Specification Document
                                                                  CO1H1370035000 PDF Specification Document
                                                                  CO1H1370039012 PDF Specification Document
                                                                  CO1H1370039029 PDF Specification Document
                                                                  CO1I1370031000 PDF Specification Document
                                                                  CO1I1370035000 PDF Specification Document
                                                                  CO1I1370039012 PDF Specification Document
                                                                  CO1I1370039029 PDF Specification Document

                                                                  Certificates

                                                                  Title