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102584 Caffeine

EMPROVE® ESSENTIAL Ph Eur,BP,USP

Caffeine MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 7-Methyltheobromine, 1,3,7-Trimethylxanthine, 3,7-Dihydro-1,3,7-trimethyl-1H-purine-2,6-dione

CAS #: 58-08-2 EC Number: 200-362-1 Molar Mass: 194.19 g/mol Hill Formula: C₈H₁₀N₄O₂ Grade: Ph Eur,BP,USP
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102584
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Overview

Replacement Information

Key Spec Table

CAS #EC NumberHill FormulaMolar MassGrade Value
58-08-2200-362-1C₈H₁₀N₄O₂194.19 g/molPh Eur,BP,USP

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                  Description
                  Catalogue Number102584
                  Synonyms7-Methyltheobromine, 1,3,7-Trimethylxanthine, 3,7-Dihydro-1,3,7-trimethyl-1H-purine-2,6-dione
                  References
                  Product Information
                  CAS number58-08-2
                  EC index number613-086-00-5
                  EC number200-362-1
                  GradePh Eur,BP,USP
                  Hill FormulaC₈H₁₀N₄O₂
                  Molar Mass194.19 g/mol
                  HS Code2939 30 10
                  Structure formula ImageStructure formula Image
                  Quality LevelMQ500
                  Applications
                  Biological Information
                  Physicochemical Information
                  Density1.23 g/cm3 (18 °C)
                  Ignition temperature>600 °C
                  Melting Point235 - 239 °C
                  pH value5.5 - 6.5 (10 g/l, H₂O, 20 °C)
                  Vapor pressure20 hPa (80 °C)
                  Bulk density220 kg/m3
                  Solubility20 g/l
                  Dimensions
                  Materials Information
                  Toxicological Information
                  LD 50 oralLD50 Rat 367.7 mg/kg
                  Safety Information according to GHS
                  Hazard Pictogram(s) Hazard Pictogram(s)
                  Hazard Statement(s)H302: Harmful if swallowed.
                  Precautionary Statement(s)P264: Wash skin thoroughly after handling.
                  P270: Do not eat, drink or smoke when using this product.
                  P301 + P312: IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell.
                  P501: Dispose of contents/ container to an approved waste disposal plant.
                  Signal WordWarning
                  Storage class10 - 13 Other liquids and solids
                  WGKWGK 1 slightly hazardous to water
                  Disposal3
                  Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
                  Safety Information
                  Categories of dangerharmful
                  Product Usage Statements
                  Storage and Shipping Information
                  StorageStore at +2°C to +30°C.
                  Packaging Information
                  Transport Information
                  Declaration (railroad and road) ADR, RIDKein Gefahrgut
                  Declaration (transport by air) IATA-DGRNo Dangerous Good
                  Declaration (transport by sea) IMDG-CodeNo Dangerous Good
                  Supplemental Information
                  Specifications
                  Assay (perchloric acid titration, calculated on dried substance)98.5 - 101.5 %
                  Assay (HPLC, calc. on anhydrous substance)98.5 - 101.0 %
                  Identity (IR)passes test
                  Identity (HPLC)passes test
                  Identity (wet chemistry)passes test
                  Identity (Melting point)234 - 239 °C
                  Appearance of solution (1 %; water)passes test
                  Aciditypasses test
                  Sulfate (SO₄)≤ 500 ppm
                  Chloroform (HS-GC)≤ 60 ppm
                  Related substances (HPLC, EP) (Highest single impurity)≤ 0.10 %
                  Related substances (HPLC, EP) (Sum of all impurities)≤ 0.10 %
                  Chromatographic purity (USP) (Highest single impurity)≤ 0.1 %
                  Chromatographic purity (USP) (Sum of all impurities)≤ 0.1 %
                  Theophylline (HPLC)≤ 0.10 %
                  Other residual solvents (ICH Q3C)excluded by the manufacturing process
                  Sulfated ash≤ 0.1 %
                  Loss on Drying (105 °C)≤ 0.5 %
                  Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
                  Corresponds to Ph Eur, BP, USP
                  Global Trade Item Number
                  Catalogue Number GTIN
                  1025841000 04022536034980
                  1025849050 04022536035000
                  CO1E1025841000 04061839009332
                  CO1E1025849050 04061839801936

                  Documentation

                  Material Qualification Dossier

                  TitleVersion
                  6.0

                  Operational Excellence Dossier

                  Title

                  Caffeine SDS

                  Title

                  Safety Data Sheet (SDS) 

                  Caffeine Certificates of Analysis

                  Product Number PackagingSpecificationLot Number
                  1025841000 Plastic bottlePDF Specification Document
                  1025849050 Fibre cartonPDF Specification Document
                  CO1E1025841000 PDF Specification Document
                  CO1E1025849050 PDF Specification Document

                  Certificates

                  Title