Pharmail

Eshmuno® CPX media for high-production downstream bioprocessing

The key challenge during intermediate purification and polishing is the ability to remove impurities similar to the target molecule, even at high loading levels. With Eshmuno® CPX media, you can efficiently remove mAb dimers and higher molecular weight species, as well as impurities such as viruses, host cell proteins, and leached Protein A. This allows purification of post Protein A mAb pools at elevated protein loads without the loss of separation selectivity.

The latest addition to our Eshmuno® resin family is a strong cation exchanger exhibiting high aggregate removal efficiency combined with high dynamic binding capacity. Built on our proven tentacle technology, Eshmuno® CPX media helps to ensure high process stability thanks to its wide pH and conductivity operating window.

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In This Same Issue:

• TRIS and phosphate buffer test kits now available
• Cellvento™ CHO-200 medium for fed-batch mode
• New USP standards for elemental impurities
• Our full-service liquid formulation offering

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