Affinity Chromatography

Maximize Your Productivity at the CAPTURE Step with Affinity Resins.

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At the capture phase of purification, the primary goals are to isolate the target molecule as quickly as possible from the clarified feedstock, reduce the process volume to a manageable scale for subsequent steps, and maximize yield and economy.

Affinity chromatography, a method of separating biochemical mixtures based on a highly specific interaction, can effectively achieve these goals.

Our range of affinity resins is designed for cost effective, high throughput purification of monoclonal, polyclonal and engineered antibodies and are especially suited for large-scale purification of today’s higher titer therapeutic antibodies.

Affinity Chromatography Resins from Merck

• Eshmuno® A resin – a rigid, high capacity, acid and alkaline resistant Protein A affinity chromatography media for the purification of Fc-containing proteins, including but not limited to monoclonal antibodies
  
  
• Fractogel® Metal Chelate resin – tentacle media for reliable purification and more economical processes