Custom Premix Selecting "Custom Premix" option means that all of the beads you have chosen will be premixed in manufacturing before the kit is sent to you.
A Na+ channel opener. Increases intracellular Ca2+ levels without affecting Na+ - Ca2+ exchange. Acts at neurotoxin receptor site 2 and preferentially binds to activated Na+ channels causing persistent activation. Induces cell death in bovine chromaffin cells.
Catalogue Number
676950
Brand Family
Calbiochem®
References
References
Maroto, R., et al. 1994. Eur. J. Pharmacol. 270, 331. Plattner, H., et al. 1994. J. Membr. Biol. 142, 229. Rando, T.A., et al. 1989. J. Gen. Physiol.93, 43. Rando, T.A., et al. 1986. Mol. Pharmacol.29, 467.
Very toxic by inhalation, in contact with skin and if swallowed.
S Phrase
S: 26-36/37/39-45
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing, gloves and eye/face protection. In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
Product Usage Statements
Storage and Shipping Information
Ship Code
Ambient Temperature Only
Toxicity
Highly Toxic
Hazardous Materials Attention:
Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Storage
+2°C to +8°C
Do not freeze
Ok to freeze
Special Instructions
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Maroto, R., et al. 1994. Eur. J. Pharmacol. 270, 331. Plattner, H., et al. 1994. J. Membr. Biol. 142, 229. Rando, T.A., et al. 1989. J. Gen. Physiol.93, 43. Rando, T.A., et al. 1986. Mol. Pharmacol.29, 467.
数据表
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
Revision
22-January-2018 JSW
Description
A Na+ channel opener. Increases intracellular Ca2+ levels without affecting Na+-Ca2+ exchange. Acts at neurotoxin receptor site 2 and preferentially binds to activated Na+ channels causing persistent activation. Induces cell death in bovine chromaffin cells.
Form
White to yellow solid
CAS number
71-62-5
RTECS
YX5600000
Chemical formula
C₃₆H₅₁NO₁₁
Structure formula
Purity
≥98% by TLC
Solubility
DMSO (25 mg/ml) or Ethanol (25 mg/ml)
Storage
+2°C to +8°C
Do Not Freeze
Ok to freeze
Special Instructions
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity
Highly Toxic
Merck USA index
14, 9954
References
Maroto, R., et al. 1994. Eur. J. Pharmacol. 270, 331. Plattner, H., et al. 1994. J. Membr. Biol. 142, 229. Rando, T.A., et al. 1989. J. Gen. Physiol.93, 43. Rando, T.A., et al. 1986. Mol. Pharmacol.29, 467.
