662086 Sigma-AldrichUCH-L1 Inhibitor - CAS 668467-91-2 - Calbiochem
The UCH-L1 Inhibitor, also referenced under CAS 668467-91-2, controls the biological activity of UCH-L1. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
More>> The UCH-L1 Inhibitor, also referenced under CAS 668467-91-2, controls the biological activity of UCH-L1. This small molecule/inhibitor is primarily used for Protease Inhibitors applications. Less<<MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
同义词: LDN-57444, Ubiquitin C-Terminal Hydrolase L1 Inhibitor, Ubiquitin C-Terminal Esterase L1 Inhibitor, Ubiquitin Thiolesterase L1 Inhibitor
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概述
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重要规格表
| CAS # | Empirical Formula |
|---|---|
| 668467-91-2 | C₁₇H₁₁Cl₃N₂O₃ |
Products
| 产品目录编号 | 包装 | 数量 / 包装 | |
|---|---|---|---|
| 662086-10MGCN | 玻璃瓶 | 10 mg |
| Description | |
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| Overview | An isatin O-acyl oxime compound that acts as a potent, reversible, competitive, and active site-directed inhibitor of UCH-L1 (Ki = 0.40 µM; IC50 = 0.88 µM) with ~28-fold greater selectivity over UCH-L3 (Cat. No. 662090). Shown to increase proliferation of UCH-L1 expresssing tumor cell line SH-SY5Y at 5 µM. A useful tool for studying the roles of UCH-L1 in cancer, Parkinson’s disease, and other neurological disorders. Permeability may vary from cell type to cell type. |
| Catalogue Number | 662086 |
| Brand Family | Calbiochem® |
| Synonyms | LDN-57444, Ubiquitin C-Terminal Hydrolase L1 Inhibitor, Ubiquitin C-Terminal Esterase L1 Inhibitor, Ubiquitin Thiolesterase L1 Inhibitor |
| References | |
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| References | Liu, Y., et al. 2003. Chem. Biol. 10, 837. |
| Product Information | |
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| CAS number | 668467-91-2 |
| ATP Competitive | Y |
| Form | Orange solid |
| Hill Formula | C₁₇H₁₁Cl₃N₂O₃ |
| Chemical formula | C₁₇H₁₁Cl₃N₂O₃ |
| Reversible | Y |
| Structure formula Image | |
| Quality Level | MQ100 |
| Applications |
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| Biological Information | |
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| Primary Target | UCH-L1 |
| Primary Target IC<sub>50</sub> | 0.88 µM |
| Primary Target K<sub>i</sub> | 0.40 µM |
| Purity | ≥95% by HPLC |
| Physicochemical Information | |
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| Cell permeable | N |
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| Packaging Information | |
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| Packaged under inert gas | Packaged under inert gas |
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| Specifications |
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| Global Trade Item Number | |
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| 产品目录编号 | GTIN |
| 662086-10MGCN | 04055977261134 |
Documentation
UCH-L1 Inhibitor - CAS 668467-91-2 - Calbiochem MSDS
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UCH-L1 Inhibitor - CAS 668467-91-2 - Calbiochem 分析证书
| 标题 | 批号 |
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| 662086 |
参考
| 参考信息概述 |
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| Liu, Y., et al. 2003. Chem. Biol. 10, 837. |