616520 Sigma-AldrichTRPV4 Antagonist I, RN-1734 - CAS 946387-07-1 - Calbiochem
The TRPV4 Antagonist I, RN-1734, also referenced under CAS 946387-07-1, controls the biological activity of TRPV4. This small molecule/inhibitor is primarily used for Biochemicals applications.
More>> The TRPV4 Antagonist I, RN-1734, also referenced under CAS 946387-07-1, controls the biological activity of TRPV4. This small molecule/inhibitor is primarily used for Biochemicals applications. Less<<MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
同义词: 2,4-Dichloro-N-isopropyl-N-(2-isopropylaminoethyl)benzenesulfonamide, Transient Receptor Potential Vanilloid-4 Antagonist I, RN1734
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概述
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重要规格表
| CAS # | Empirical Formula |
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| 946387-07-1 | C₁₄H₂₂Cl₂N2O₂S |
Products
| 产品目录编号 | 包装 | 数量 / 包装 | |
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| 616520-10MGCN | 玻璃瓶 | 10 mg |
| Description | |
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| Overview | A cell-permeable benzenesulfonamide compound that selectively antagonizes TRPV4 agonist 4α-PDD- (Cat. No. 524394) stimulated Ca2+ influx (IC50 = 2.3, 3.2 and 5.9 µM, respectively, in HEK293 expressing human, rat, or mouse TRPV4) without affecting the activity of three other human TRP (transient receptor potential) channels, including capsaicin- (Cat. No. 211275) activated TRPV1, camphor-activated TRPV3, and methanol-activated TRPM8 (IC50 >30 µM). |
| Catalogue Number | 616520 |
| Brand Family | Calbiochem® |
| Synonyms | 2,4-Dichloro-N-isopropyl-N-(2-isopropylaminoethyl)benzenesulfonamide, Transient Receptor Potential Vanilloid-4 Antagonist I, RN1734 |
| References | |
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| References | Vincent, F., et al. 2009. Biochem. Biophys. Res. Commun. 389, 490. |
| Product Information | |
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| CAS number | 946387-07-1 |
| Form | Yellow solid |
| Hill Formula | C₁₄H₂₂Cl₂N2O₂S |
| Chemical formula | C₁₄H₂₂Cl₂N2O₂S |
| Structure formula Image | |
| Quality Level | MQ100 |
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| Biological Information | |
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| Purity | ≥95% by HPLC |
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| Packaged under inert gas | Packaged under inert gas |
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| Specifications |
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| Global Trade Item Number | |
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| 产品目录编号 | GTIN |
| 616520-10MGCN | 04055977185249 |
Documentation
TRPV4 Antagonist I, RN-1734 - CAS 946387-07-1 - Calbiochem MSDS
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TRPV4 Antagonist I, RN-1734 - CAS 946387-07-1 - Calbiochem 分析证书
| 标题 | 批号 |
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| 616520 |
参考
| 参考信息概述 |
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| Vincent, F., et al. 2009. Biochem. Biophys. Res. Commun. 389, 490. |
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Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
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