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5677 Spermine, Tetrahydrochloride - CAS 306-67-2 - Calbiochem

Polyamine that plays an important role in the regulation of cellular proliferation and differentiation.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
5677
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概述

Replacement Information

重要规格表

CAS #Empirical Formula
306-67-2C₁₀H₂₆N₄ . 4HCl

Products

产品目录编号包装 数量 / 包装
5677-5GMCN 塑胶安瓿;塑胶针药瓶 5 gm
Description
OverviewPolyamine that plays an important role in the regulation of cellular proliferation and differentiation. Has both stimulatory and inhibitory effects on NMDA receptors depending on the subunit composition of the receptor. Acts as an inhibitor of phospholipase Cα and an activator of phospholipase Cδ. Inhibits DNA fragmentation and morphological apoptosis. Inhibits neuronal NOS.
Catalogue Number5677
Brand Family Calbiochem®
References
ReferencesIgarashi, K. and Williams, K. 1995. J. Pharmacol. Exp. Ther. 272, 1101.
Escargueil-Blanc, I., et al. 1994. FASEB J. 8, 1075.
Hu, J., et al. 1994. Neurosci. Lett. 175, 41.
Tompkins, T.A. and Moscarello, M.A. 1994. Biochim. Biophys. Acta 1206, 1208.
Trubiani, O., et al. 1994. Biochem. Mol. Biol. Int. 32, 1085.
Svensson, F., et al. 1993. Mol. Cell. Biochem. 124, 141.
Ask, A., et al. 1992. Cancer Lett. 66, 29.
Chida, N., et al. 1992. Brain Res. 593, 57.
Khan, A.U., et al. 1992. Proc. Natl. Acad. Sci. USA 89, 11428.
Messena, L., et al. 1992. J. Leukoc. Biol. 52, 585.
Pawelczyk, T., et al. 1992. Arch. Biochem. Biophys. 297, 328.
Shantz, L.M., et al. 1992. Biochem. J. 288, 511.
Product Information
CAS number306-67-2
FormWhite solid
Hill FormulaC₁₀H₂₆N₄ . 4HCl
Chemical formulaC₁₀H₂₆N₄ . 4HCl
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary Targetphospholipase C α
Secondary targetnNOS
Purity≥99% by titration
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
RTECSEJ7230000
Safety Information
R PhraseR: 36/37/38

Irritating to eyes, respiratory system and skin.
S PhraseS: 26-36

In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing.
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Irritant
Storage +15°C to +30°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot, purge with inert gas, and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C under inert gas.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
产品目录编号 GTIN
5677-5GMCN 04055977190939

Documentation

Spermine, Tetrahydrochloride - CAS 306-67-2 - Calbiochem MSDS

职位

物料安全数据表 (MSDS) 

Spermine, Tetrahydrochloride - CAS 306-67-2 - Calbiochem 分析证书

标题批号
5677

参考

参考信息概述
Igarashi, K. and Williams, K. 1995. J. Pharmacol. Exp. Ther. 272, 1101.
Escargueil-Blanc, I., et al. 1994. FASEB J. 8, 1075.
Hu, J., et al. 1994. Neurosci. Lett. 175, 41.
Tompkins, T.A. and Moscarello, M.A. 1994. Biochim. Biophys. Acta 1206, 1208.
Trubiani, O., et al. 1994. Biochem. Mol. Biol. Int. 32, 1085.
Svensson, F., et al. 1993. Mol. Cell. Biochem. 124, 141.
Ask, A., et al. 1992. Cancer Lett. 66, 29.
Chida, N., et al. 1992. Brain Res. 593, 57.
Khan, A.U., et al. 1992. Proc. Natl. Acad. Sci. USA 89, 11428.
Messena, L., et al. 1992. J. Leukoc. Biol. 52, 585.
Pawelczyk, T., et al. 1992. Arch. Biochem. Biophys. 297, 328.
Shantz, L.M., et al. 1992. Biochem. J. 288, 511.

小册子

标题
Caspases and other Apoptosis Related Tools Brochure
Excitotoxic Glutamate Analogs Technical Bulletin
数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision08-October-2007 JSW
DescriptionPolyamine that plays an important role in the regulation of cellular proliferation and differentiation. Acts as an inhibitor of phopholipase C-α and an activator of phopholipase C-δ. Has both stimulatory and inhibitory effects on NMDA receptors depending on the subunit composition of the receptor. Inhibits neuronal NOS. Inhibits DNA fragmentation and morphological apoptosis.
FormWhite solid
CAS number306-67-2
RTECSEJ7230000
Chemical formulaC₁₀H₂₆N₄ . 4HCl
Structure formulaStructure formula
Purity≥99% by titration
SolubilityH₂O (20 mg/ml)
Storage +15°C to +30°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot, purge with inert gas, and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C under inert gas.
Toxicity Irritant
Merck USA index14, 8743
ReferencesIgarashi, K. and Williams, K. 1995. J. Pharmacol. Exp. Ther. 272, 1101.
Escargueil-Blanc, I., et al. 1994. FASEB J. 8, 1075.
Hu, J., et al. 1994. Neurosci. Lett. 175, 41.
Tompkins, T.A. and Moscarello, M.A. 1994. Biochim. Biophys. Acta 1206, 1208.
Trubiani, O., et al. 1994. Biochem. Mol. Biol. Int. 32, 1085.
Svensson, F., et al. 1993. Mol. Cell. Biochem. 124, 141.
Ask, A., et al. 1992. Cancer Lett. 66, 29.
Chida, N., et al. 1992. Brain Res. 593, 57.
Khan, A.U., et al. 1992. Proc. Natl. Acad. Sci. USA 89, 11428.
Messena, L., et al. 1992. J. Leukoc. Biol. 52, 585.
Pawelczyk, T., et al. 1992. Arch. Biochem. Biophys. 297, 328.
Shantz, L.M., et al. 1992. Biochem. J. 288, 511.