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14-702M Rsk4 Protein, active, 250 µg

Active, 6His-tagged, recombinant, full length, human Rsk4, for use in Kinase Assays.

14-702M
250 µg  Also available in 10 μg size (cat#14-702) and in bulk (cat# 14-702-K).
Purchase on Sigma-Aldrich

概述

Replacement Information
Description
Catalogue Number14-702M
Brand Family Upstate
Trade Name
  • Upstate
DescriptionRsk4 Protein, active, 250 µg
Overview6His-tagged, recombinant, full length, human Rsk4
References
Product Information
Quality LevelMQ300
Applications
ApplicationActive, 6His-tagged, recombinant, full length, human Rsk4, for use in Kinase Assays.
Key Applications
  • Kinase Assay
Biological Information
Sourceexpressed by baculovirus in Sf21 cells
Specific ActivityFor Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Entrez Gene Number
Gene Symbol
  • RPS6KA6
  • RSK4
  • pp90RSK4
  • RSK-4
Protein TargetRsk4
Purification MethodNi2+/NTA-agarose
Target Sub-FamilyAGC
UniProt Number
UniProt SummaryFUNCTION: SwissProt: Q9UK32 # Serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB.
COFACTOR: Magnesium (By similarity).
SIZE: 745 amino acids; 83872 Da
SUBUNIT: Forms a complex with either ERK1 or ERK2 in quiescent cells. Transiently dissociates following mitogenic stimulation (By similarity).
PTM: Autophosphorylated on Ser-389, as part of the activation process (By similarity).
SIMILARITY: SwissProt: Q9UK32 ## Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. & Contains 1 AGC-kinase C-terminal domain. & Contains 2 protein kinase domains.
Molecular Weight85.2kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assuranceroutinely evaluated by phosphorylation of PAKtide (RRRLSFAEPG)
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions6 months at -70°C from date of shipment
Packaging Information
Material Size250 µg
Material PackageAlso available in 10 μg size (cat#14-702) and in bulk (cat# 14-702-K).
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
产品目录编号 GTIN
14-702M 04053252511677

Documentation

相关产品和应用

Alternative Packsize

产品目录编号 描述
14-702 Rsk4 Protein, active, 10 µg

产品族

Kinase & Phosphatase Products

Millipore offers a large portfolio of Kinases, Phophatases, Substrates, Inhibitors, Kits, reagents & tools for Signaling research. See below for a list of these products, in multiple pack sizes.
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种类

Life Science Research > Proteins and Enzymes > Purified Kinases
Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Purified Kinases