ProSep® Ultra Plus Chromatography Media
Designed for high throughput affinity purification of monoclonal antibodies and other proteins.
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概述
规格
订货信息
Documentation
参考
| 参考概述 | 应用 |
|---|---|
| Determining the Useful Lifetime of Chromatography Resins: Prospective Small-Scale Studies O’Leary et al.,Biopharm, September 2001, pp 10 -18 Biopharm, September 2001, pp 10 -18 2001 | |
| Pressure-flow relationships for packed beds of compressible chromatography media at laboratory and production scale Stickel J.J.; Fotopoulos A. Biotechnology Progress, 17/4 (744-751), 2001 2001 | Process development studies |
| Determining the useful lifetime chromatography resins: Prospective small-scale studies O'Leary R.M.; Feuerhelm D.; Peers D.; Xu Y.; Blank G.S. BioPharm ( BIOPHARM ) (United States) 2001, 14/9 (10-18) 2001 | Process development studies |
| Affinity chromatography is vital to protein research and development Curling JM,BIOPHARM-THE APPLIED TECHNOLOGIES OF BIOPHARMACEUTICAL DEVELOPMENT , 2001, V14, N10 (OCT), P51-52 BIOPHARM-THE APPLIED TECHNOLOGIES OF BIOPHARMACEUTICAL DEVELOPMENT , 2001, V14, N10 (OCT), P51-52 2001 | Process development studies |
| Industrial purification of pharmaceutical antibodies: development, operation, and validation of chromatography processes. Fahrner RL, Knudsen HL, Basey CD, Galan W, Feuerhelm D, Vanderlaan M, Blank GS. Biotechnol Genet Eng Rev 2001;18:301-27 2001 | Process development studies |
| Preparative Immunoaffinity Techniques Michael Price and Kami Beyzavi; Peptide Antigens, A Practical Approach, Chapter 5 Peptide Antigens, A Practical Approach, Chapter 5 1999 | |
| Performance comparison of Protein A affinity chromatography adsorbents for purifying recombinant monoclonal antibodies Robert L Fahrner, Duncan H Whitney, Martin Vanderlaan, Gregory S Blank. Biotechnol. Appl. Biochem, Vol 30 121-128, 1999 1999 | |
| Performance comparison of Protein A affinity-chromatography sorbents for purifying recombinant monoclonal antibodies Fahrner, et al.,Biotechnol. Appl. Biochem. (1999) 30, 121-128 Biotechnol. Appl. Biochem. (1999) 30, 121-128 1999 | |
| The optimal flow rate and column length for maximum production rate of Protein A affinity chromatography R.L Fahrner, H.V. Iyer, G.S. Blank Bioprocess Engineering 21 (1999) 287-292 - Springer-Verlag. 1999 | Process development studies |
| Development, validation and application of an ultra-sensitive two-site enzyme immunoassay for human follistatin LW Evans, S Muttukrishna and NP Groome Journal of Endocrinology, 156, 275-282, 1998 1998 |
问与答
| 问题 | 回答 |
|---|---|
| What is the difference between ProSep-vA Ultra and ProSep-vA High Capacity chromatography media? | Prosep-vA Ultra uses a 700 angstrom pore size porous glass and ProSep vA High Capacity uses a 1000 Angstrom porous glass. The Prosep-vA Ultra has a greater surface area due to the smaller pore size, which allows the immobilization of a larger amount of protein A. The increased amount of protein A results in a higher capacity resin. |
| How do I choose between ProSep-vA Ultra versus ProSep-vA High Capacity? | Prosep-vA Ultra has a higher binding capacity than ProSep-vA High Capacity - ≥ 56mg/ml vs ≥ 40 mg/ml. ProSep-vA High Capacity has a larger pore size and may perform better when purifying fusion proteins or antibody conjugates with molecular weights above 150 kD. |
| What is the shelf life of the Prosep-A family of protein A affinity media? | One Year. Shelf life studies are ongoing and will be increased as data becomes available. Please contact Technical Service for further shelf life information. |
| What is Prosep-vA ? | ProSep-vA is native protein A derived from Staphylococcus aureus which has been immobilized onto porous glass beads. ProSep-vA is available on glass of two diffferent porosities - ProSep-vA ultra (700 angstroms) and ProSep-vA High Capacity (1000 angstroms) |
| Do you provide reguatory support? | A regulatory reference document is available for ProSep-vA High Capacity and will soon be available for Prosep-vA Ultra. As the raw materials and the chemistry used in the manufacture of ProSep-vA Ultra are the same as for ProSep-vA High Capacity , the regulators will be familiar with the product. ProSep-vA High Capacity has been and is widely used in various licensed MAb products and products in clinical trails. |
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相关产品，按下列排序： Application Facete
| Antibody Purification |
| Protein Purification |
| HPLC High Performance Liquid Chromatography |
相关产品，按下列排序： Brand Facete
| ProSep® |
种类
| Biopharmaceutical Manufacturing > Downstream Processing > Chromatography > Affinity Chromatography |