Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

525276 Phosphoramidon, Disodium Salt - Calbiochem

Inhibits some metalloendopeptidases.

Phosphoramidon, Disodium Salt - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

同义词: N-(α-Rhamnopyranosyloxyhydroxyphosphinyl)-L-leucyl-L-tryptophan, 2Na

Primary Target: thermolysin
525276
Purchase on Sigma-Aldrich

概述

Replacement Information

重要规格表

Empirical Formula
C₂₃H₃₂N₃O₁₀P · 2Na

Products

产品目录编号包装 数量 / 包装
525276-5MGCN 塑胶安瓿;塑胶针药瓶 5 mg
Description
OverviewInhibits some metalloendopeptidases. Highly specific inhibitor of thermolysin. Inhibits the conversion of big endothelin-1 to endothelin (IC50 = 4.6 µM).
Effective concentration: 1-10 µM.
Catalogue Number525276
Brand Family Calbiochem®
SynonymsN-(α-Rhamnopyranosyloxyhydroxyphosphinyl)-L-leucyl-L-tryptophan, 2Na
References
ReferencesBalwierczxak, J.L., et al. 1995. Biochem. Pharmacol. 49, 291.
Howell, S., et al. 1993. Biochem. J. 290, 159.
Product Information
ATP CompetitiveN
FormWhite lyophilized solid
Hill FormulaC₂₃H₃₂N₃O₁₀P · 2Na
Chemical formulaC₂₃H₃₂N₃O₁₀P · 2Na
Hygroscopic Hygroscopic
ReversibleN
Quality LevelMQ100
Applications
Biological Information
Primary Targetthermolysin
Primary Target IC<sub>50</sub>4.6 µM against the conversion of big endothelin-1 to endothelin
PuritySingle spot by TLC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage +2°C to +8°C
Protect from Light Protect from light
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
产品目录编号 GTIN
525276-5MGCN 04055977270648

Documentation

Phosphoramidon, Disodium Salt - Calbiochem MSDS

职位

物料安全数据表 (MSDS) 

Phosphoramidon, Disodium Salt - Calbiochem 分析证书

标题批号
525276

参考

参考信息概述
Balwierczxak, J.L., et al. 1995. Biochem. Pharmacol. 49, 291.
Howell, S., et al. 1993. Biochem. J. 290, 159.

引用

标题
  • Peter Oishi, et al. (2006) Nitric Oxide-Endothelin-1 Interactions After Surgically Induced Acute Increases in Pulmonary Blood Flow in the Intact Lamb. American Journal of Physiology Heart and Circulatory Physiology 290, H1922-1932.
  • Anthony R. White, et al. (2006) Degradation of the alzheimer disease amyloid -peptide by metal-dependent up-regulation of metalloprotease activity. journal of Biological Chemistry 281, 17670-17680.
    		•
    数据表

    Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

    Revision26-August-2008 RFH
    SynonymsN-(α-Rhamnopyranosyloxyhydroxyphosphinyl)-L-leucyl-L-tryptophan, 2Na
    DescriptionInhibits some metalloendopeptidases. Highly specific inhibitor of thermolysin. Inhibits the conversion of big endothelin-1 to endothelin (IC50 = 4.6 µM).
    FormWhite lyophilized solid
    Chemical formulaC₂₃H₃₂N₃O₁₀P · 2Na
    PuritySingle spot by TLC
    SolubilityDMSO (10 mg/ml), methanol, or H₂O
    Storage Protect from light
    +2°C to +8°C
    Hygroscopic
    Do Not Freeze Ok to freeze
    Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
    Toxicity Standard Handling
    ReferencesBalwierczxak, J.L., et al. 1995. Biochem. Pharmacol. 49, 291.
    Howell, S., et al. 1993. Biochem. J. 290, 159.
    Citation
  • Peter Oishi, et al. (2006) Nitric Oxide-Endothelin-1 Interactions After Surgically Induced Acute Increases in Pulmonary Blood Flow in the Intact Lamb. American Journal of Physiology Heart and Circulatory Physiology 290, H1922-1932.
  • Anthony R. White, et al. (2006) Degradation of the alzheimer disease amyloid -peptide by metal-dependent up-regulation of metalloprotease activity. journal of Biological Chemistry 281, 17670-17680.
    		•