528110 MilliporePIH - CAS 737-86-0 - Calbiochem
A cell-permeable, non-toxic tridendate iron (Fe3+) chelator of the aroyl hydrazone class.
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同义词: pyridoxal isonicotinoyl hydrazone, Iron Chelator III
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概述
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重要规格表
| CAS # | Empirical Formula |
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| 737-86-0 | C₁₄H₁₄N₄O₃ |
Products
| 产品目录编号 | 包装 | 数量 / 包装 | |
|---|---|---|---|
| 528110-50MGCN | 塑胶安瓿;塑胶针药瓶 | 50 mg |
| Description | |
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| Overview | A cell-permeable, non-toxic tridendate iron (Fe3+) chelator of the aroyl hydrazone class. Even at low concentrations, highly effective in mobilizing Fe3+ from cells and preventing its uptake from transferrin, even at low concentrations. Exhibits similar specificity and binding affinity as Deferoxamine Mesylate (Cat. No. 252750) but has greater access to mitochondrial iron. Also useful for the management of iron overload disease in experimental models. Inhibits the induction of heme containing indoleamine 2,3-dioxygenase activity. |
| Catalogue Number | 528110 |
| Brand Family | Calbiochem® |
| Synonyms | pyridoxal isonicotinoyl hydrazone, Iron Chelator III |
| Product Information | |
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| CAS number | 737-86-0 |
| Form | Yellow solid |
| Hill Formula | C₁₄H₁₄N₄O₃ |
| Chemical formula | C₁₄H₁₄N₄O₃ |
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| Quality Level | MQ100 |
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| Purity | ≥99% by HPLC |
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| Packaged under inert gas | Packaged under inert gas |
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| Specifications |
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| 产品目录编号 | GTIN |
| 528110-50MGCN | 04055977270518 |
Documentation
PIH - CAS 737-86-0 - Calbiochem MSDS
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PIH - CAS 737-86-0 - Calbiochem 分析证书
| 标题 | 批号 |
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| 528110 |
参考
| 参考信息概述 |
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| Buss, J.L., et al. 2002. Biochem. Pharmacol. 64, 1689. Thomas, S.R., et al. 2001. J. Immunol. 166, 6332. Hermes-Linda, M., et al. 2000. Biochim. Biophys. Acta 1523, 154. Blaha, K., et al. 1998. Blood 11, 4368. Richardson, D.R., and Ponka, P. 1998. J. Lab. Clin. Med. 131, 306. Richardson, D.R.,et al. 1995. Blood 86, 4295. Richardson, D.R., et al. 1994. J. Lab. Clin. Med. 124, 660. Ponka, P., et al. 1988. Biochim. Biophys. Acta 967, 122. Ponka, P., et al. 1984. Biochim. Biophys. Acta 802, 477. Ponka, P., et al. 1979. FEBS Lett. 97, 317. |