513040 Sigma-AldrichPD 174265 - CAS 216163-53-0 - Calbiochem
A potent, cell-permeable, reversible, ATP-competitive and selective inhibitor of EGF receptor (EGFR) tyrosine kinase activity (IC₅₀ = 450 pM).
More>> A potent, cell-permeable, reversible, ATP-competitive and selective inhibitor of EGF receptor (EGFR) tyrosine kinase activity (IC₅₀ = 450 pM). Less<<PD 174265 - CAS 216163-53-0 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
同义词: 4-[(3-Bromophenyl)amino]-6-propionylamidoquinazoline
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概述
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重要规格表
| CAS # | Empirical Formula |
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| 216163-53-0 | C₁₇H₁₅BrN₄O |
Products
| 产品目录编号 | 包装 | 数量 / 包装 | |
|---|---|---|---|
| 513040-1MGCN | 塑胶安瓿;塑胶针药瓶 | 1 mg |
| Description | |
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| Overview | A potent, cell-permeable, reversible, ATP-competitive and selective inhibitor of EGF receptor (EGFR) tyrosine kinase activity (IC50 = 450 pM). The reversible nature of this compound makes it a less effective antitumor agent than PD 168393 (Cat. No. 513033). |
| Catalogue Number | 513040 |
| Brand Family | Calbiochem® |
| Synonyms | 4-[(3-Bromophenyl)amino]-6-propionylamidoquinazoline |
| References | |
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| References | Fry, D.W., et al. 1998. Proc. Natl. Acad. Sci. USA 95, 12022. |
| Product Information | |
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| CAS number | 216163-53-0 |
| ATP Competitive | Y |
| Form | Yellow solid |
| Hill Formula | C₁₇H₁₅BrN₄O |
| Chemical formula | C₁₇H₁₅BrN₄O |
| Reversible | Y |
| Structure formula Image | |
| Quality Level | MQ100 |
| Applications |
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| Biological Information | |
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| Primary Target | EGFR tyrosine kinase activity |
| Primary Target IC<sub>50</sub> | 450 pM against EGF receptor (EGFR) tyrosine kinase activity |
| Purity | ≥97% by HPLC |
| Physicochemical Information | |
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| Cell permeable | Y |
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| Packaging Information | |
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| Packaged under inert gas | Packaged under inert gas |
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| Specifications |
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| Global Trade Item Number | |
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| 产品目录编号 | GTIN |
| 513040-1MGCN | 04055977198669 |
Documentation
PD 174265 - CAS 216163-53-0 - Calbiochem MSDS
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PD 174265 - CAS 216163-53-0 - Calbiochem 分析证书
| 标题 | 批号 |
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| 513040 |
参考
| 参考信息概述 |
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| Fry, D.W., et al. 1998. Proc. Natl. Acad. Sci. USA 95, 12022. |