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14-927M PAK1 Protein, active, 250 µg

Active, N-terminal FLAG-tagged, recombinant, human PAK1, amino acids 150-end. For use in Kinase Assays.

PAK1 Protein, active, 250 µg MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
14-927M
250 µg  Also available in 10μg size as catalog # 14-927 and in 250 μg as catalog # 14-927M.
Purchase on Sigma-Aldrich

概述

Replacement Information
Description
Catalogue Number14-927M
Trade Name
  • Upstate
DescriptionPAK1 Protein, active, 250 µg
OverviewThis protein is a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
References
Product Information
Presentation50mM Tris/HCl pH7.5, 150mM NaCl, 10mM β-glycerophosphate, 1mM sodium orthovanadate, 1mM NaF, 28% v/v glycerol, 0.03% Brij-35, 1mM benzamidine, 0.2mM PMSF, 0.1% 2-mercaptoethanol
Quality LevelMQ100
Applications
ApplicationActive, N-terminal FLAG-tagged, recombinant, human PAK1, amino acids 150-end. For use in Kinase Assays.
Key Applications
  • Kinase Assay
Biological Information
SourceN-terminal FLAG-tagged, recombinant, human PAK1 amino acids 150-end, expressed by baculovirus in Sf21 insect cells.
Specific ActivityFor Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Entrez Gene Number
Gene Symbol
  • PAK1
  • Alpha-PAK
  • p21-activated kinase 1
  • PAK-1
  • p65-PAK
Protein TargetPAK1
Purification MethodPurified by immunoaffinity chromatography.
Target Sub-FamilySTE
UniProt Number
Molecular Weight46 kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceRoutinely evaluated by phosphorylation of peptide RRRLSFAEPG.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions6 months at -70°C
Packaging Information
Material Size250 µg
Material PackageAlso available in 10μg size as catalog # 14-927 and in 250 μg as catalog # 14-927M.
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
产品目录编号 GTIN
14-927M 04053252851490

相关产品和应用

Alternative Packsize

产品目录编号 描述
14-927 PAK1 Protein, active, 10 µg

产品族

Kinase & Phosphatase Products

Millipore offers a large portfolio of Kinases, Phophatases, Substrates, Inhibitors, Kits, reagents & tools for Signaling research. See below for a list of these products, in multiple pack sizes.
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种类

Life Science Research > Proteins and Enzymes > Purified Kinases
Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Purified Kinases