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491207 Novobiocin, Sodium Salt - CAS 1476-53-5 - Calbiochem

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MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Primary Target: retrovirus RNA-dependent DNA polymerases
491207
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概述

Replacement Information

重要规格表

CAS #Empirical Formula
1476-53-5C₃₁H₃₅N₂O₁₁ · Na

Products

产品目录编号包装 数量 / 包装
491207-10GMCN 玻璃瓶 10 gm
Description
OverviewDNA gyrase inhibitor used for the production of positively supercoiled plasma DNA. Inhibits retrovirus RNA-dependent DNA polymerases. Also a potent inhibitor of ADP ribosylation eliminates the wild-type pMG110 plasmid from E. coli.
Catalogue Number491207
Brand Family Calbiochem®
References
ReferencesMarcu, M.G., et al. 2000. J. Natl. Cancer Inst. 92, 242.
Luhrmann, A., et al. 1998. Antimicrob. Agents Chemotherp. 42, 1911.
Hooper, D.C., et al. 1984. Antimicrob. Agents Chemother. 25, 586.
Lockshon, D., and Morris, D.R. 1983. Nucleic Acid. Res. 11, 2999.
Sumiyoshi, Y., et al. 1983. J. Gen. Virol. 64, 2329.
Staudenbauer, W.L. 1975. J. Mol. Biol. 96, 201.
Product Information
CAS number1476-53-5
ATP CompetitiveN
FormWhite to yellow solid
Hill FormulaC₃₁H₃₅N₂O₁₁ · Na
Chemical formulaC₃₁H₃₅N₂O₁₁ · Na
ReversibleN
Quality LevelMQ100
Applications
Biological Information
Primary Targetretrovirus RNA-dependent DNA polymerases
Purity≥90% by HPLC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
RTECSRD5425000
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Harmful
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, refrigerate (4°C). Stock solutions are stable for 3 months at 4°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
产品目录编号 GTIN
491207-10GMCN 07790788050818

Documentation

Novobiocin, Sodium Salt - CAS 1476-53-5 - Calbiochem MSDS

职位

物料安全数据表 (MSDS) 

Novobiocin, Sodium Salt - CAS 1476-53-5 - Calbiochem 分析证书

标题批号
491207

参考

参考信息概述
Marcu, M.G., et al. 2000. J. Natl. Cancer Inst. 92, 242.
Luhrmann, A., et al. 1998. Antimicrob. Agents Chemotherp. 42, 1911.
Hooper, D.C., et al. 1984. Antimicrob. Agents Chemother. 25, 586.
Lockshon, D., and Morris, D.R. 1983. Nucleic Acid. Res. 11, 2999.
Sumiyoshi, Y., et al. 1983. J. Gen. Virol. 64, 2329.
Staudenbauer, W.L. 1975. J. Mol. Biol. 96, 201.
数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision22-May-2018 JSW
DescriptionA DNA gyrase inhibitor that can be used for the production of positively supercoiled plasma DNA. Targets the nucleotide-binding site of gyrase B. Exhibits antibacterial properties. Inhibits retrovirus RNA-dependent DNA polymerases. Inhibits LPS-induced production of pro-inflammatory cytokines. Reported to act as a potent inhibitor of ADP ribosylation. Also inhibits protein synthesis and alters the phosphorylation state of several cytosolic proteins.
FormWhite to yellow solid
CAS number1476-53-5
RTECSRD5425000
Chemical formulaC₃₁H₃₅N₂O₁₁ · Na
Purity≥90% by HPLC
SolubilityH₂O (50 mg/ml)
Storage Protect from light
+2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, refrigerate (4°C). Stock solutions are stable for 3 months at 4°C.
Toxicity Harmful
Merck USA index14, 6722
ReferencesMarcu, M.G., et al. 2000. J. Natl. Cancer Inst. 92, 242.
Luhrmann, A., et al. 1998. Antimicrob. Agents Chemotherp. 42, 1911.
Hooper, D.C., et al. 1984. Antimicrob. Agents Chemother. 25, 586.
Lockshon, D., and Morris, D.R. 1983. Nucleic Acid. Res. 11, 2999.
Sumiyoshi, Y., et al. 1983. J. Gen. Virol. 64, 2329.
Staudenbauer, W.L. 1975. J. Mol. Biol. 96, 201.