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AG243 Midkine, recombinant human

Midkine, recombinant human MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Key Applications: Positive Control UniProt Number: P21741 Entrez Gene Number: NM_001012333.1, NM_001012334.1, NM_002391.3
AG243
20 µg  
Purchase on Sigma-Aldrich

概述

Replacement Information
Description
Catalogue NumberAG243
Brand Family Chemicon®
Trade Name
  • Chemicon
DescriptionMidkine, recombinant human
OverviewHuman Midkine (MK) is a new member of the heparin-binding neurotrophic factor family. MK and PTN (Pleiotrophin) are structural homologs, and are highly conserved among species. MK plays important roles in development and carcinogensis and has several important biological effects, including promotion of neurite extension and neuronal survival. Recombinant Midkine is a 13.4 kDa protein, comprising of 123 amino acid residues.
References
Product Information
PresentationLyophilized from 0.4x PBS, pH 7.4.
Quality LevelMQ100
Applications
Key Applications
  • Positive Control
Biological Information
PurityGreater than 98% by SDS-PAGE and HPLC analysis. Endotoxin level is less than 0.1 ng per mg of MK.
SourceE.coli
Entrez Gene Number
Gene Symbol
  • MDK
  • ARAP
  • FLJ27379
  • MK1
  • NEGF2
  • MK
  • midkine
UniProt Number
UniProt SummaryFUNCTION: SwissProt: P21741 # Has heparin binding activity, and growth promoting activity. Involved in neointima formation after arterial injury, possibly by mediating leukocyte recruitment. Also involved in early fetal adrenal gland development (By similarity).
SIZE: 143 amino acids; 15585 Da
SUBUNIT: Homodimer.
SUBCELLULAR LOCATION: Secreted.
SIMILARITY: SwissProt: P21741 ## Belongs to the pleiotrophin family.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsThe lyophilized powder, though stable at room temperature, is best stored desiccated below 0°C. After a quick spin, reconstitute with sterile water to a concentration of 0.1-1.0 mg/mL. This solution can be diluted into water or other buffered solutions. Reconstitute MK should be stored in undiluted aliquots at -20°C for up to 6 months.
Packaging Information
Material Size20 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
产品目录编号 GTIN
AG243 04053252580970