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A neurotoxin that is a precusor of MPP+ which is toxic to dopaminergic neurons and causes Parkinsonism. Widely used in research to induce Parkinson′s disease models in primates.
Catalogue Number
506382
Brand Family
Calbiochem®
Synonyms
Dopaminergic neurotoxin, MPTP
References
References
Langston, J. W., et al. 1985. Trends in Neurosci.8, 79. Gabriel, T. L., et al. 1999. Nature Med.5, 1403. Zhang, X., et al. 2010. J. Proteome Res.9, 1496.
If swallowed, seek medical advice immediately and show this container or label.
Product Usage Statements
Storage and Shipping Information
Ship Code
Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity
Toxic
Hazardous Materials Attention:
Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Storage
+2°C to +8°C
Protect from Light
Protect from light
Do not freeze
Ok to freeze
Special Instructions
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
产品目录编号
GTIN
5.06382.0001
04055977243277
Documentation
MPTP Hydrochloride - CAS 23007-85-4 - Calbiochem MSDS
Langston, J. W., et al. 1985. Trends in Neurosci.8, 79. Gabriel, T. L., et al. 1999. Nature Med.5, 1403. Zhang, X., et al. 2010. J. Proteome Res.9, 1496.
数据表
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
Revision
31-October-2013 JSW
Synonyms
Dopaminergic neurotoxin, MPTP
Description
A neurotoxin that is a precusor of MPP+ which is toxic to dopaminergic neurons and causes Parkinsonism. Widely used in research to induce Parkinson′s disease models in primates.
Form
White solid
CAS number
23007-85-4
Chemical formula
C₁₂H₁₅N·HCl
Structure formula
Purity
≥98% by TLC
Solubility
H₂O (100 mg/ml)
Storage
Protect from light
+2°C to +8°C
Do Not Freeze
Ok to freeze
Special Instructions
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity
Toxic
References
Langston, J. W., et al. 1985. Trends in Neurosci.8, 79. Gabriel, T. L., et al. 1999. Nature Med.5, 1403. Zhang, X., et al. 2010. J. Proteome Res.9, 1496.
