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444218 MMP-3 Inhibitor I - Calbiochem

444218
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概述

Replacement Information

重要规格表

Empirical Formula
C₂₇H₄₆N₁₀O₉S

Products

产品目录编号包装 数量 / 包装
444218-5MGCN 塑胶安瓿;塑胶针药瓶 5 mg
Description
OverviewInhibits the matrix metalloproteinase MMP-3 (IC50 = 5 µM).
Catalogue Number444218
Brand Family Calbiochem®
SynonymsAc-RCGVPD-NH₂, Stromelysin-1 Inhibitor
References
ReferencesFotouhi, N., et al. 1994. J. Biol. Chem. 269, 30227.
Hanglow, A.C., et al. 1993. Agents Actions 39, C148.
Product Information
ATP CompetitiveN
FormWhite solid
FormulationSupplied as a trifluroacetate salt.
Hill FormulaC₂₇H₄₆N₁₀O₉S
Chemical formulaC₂₇H₄₆N₁₀O₉S
Hygroscopic Hygroscopic
ReversibleN
Quality LevelMQ100
Applications
Biological Information
Primary TargetMMP-3
Primary Target IC<sub>50</sub>5 µM against MMP-3
Purity≥90% by HPLC
Physicochemical Information
Cell permeableN
Peptide SequenceAc-Arg-Cys-Gly-Val-Pro-Asp-NH₂
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing recosntitution, aliquot and freeze (-20°C). Stock solutions are stable for 1-2 weeks at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
产品目录编号 GTIN
444218-5MGCN 04055977205220

Documentation

MMP-3 Inhibitor I - Calbiochem MSDS

职位

物料安全数据表 (MSDS) 

MMP-3 Inhibitor I - Calbiochem 分析证书

标题批号
444218

参考

参考信息概述
Fotouhi, N., et al. 1994. J. Biol. Chem. 269, 30227.
Hanglow, A.C., et al. 1993. Agents Actions 39, C148.

引用

标题
  • Anthony R. White, et al. (2006) Degradation of the alzheimer disease amyloid -peptide by metal-dependent up-regulation of metalloprotease activity. journal of Biological Chemistry 281, 17670-17680.
  • 数据表

    Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

    Revision31-January-2008 JSW
    SynonymsAc-RCGVPD-NH₂, Stromelysin-1 Inhibitor
    DescriptionInhibits matrix metalloproteinase-3 (stromelysin) (IC50 = 5 µM). The inhibitor is based on a segment from the conserved region of the NH2-terminal propeptide domain.
    FormWhite solid
    FormulationSupplied as a trifluroacetate salt.
    Chemical formulaC₂₇H₄₆N₁₀O₉S
    Peptide SequenceAc-Arg-Cys-Gly-Val-Pro-Asp-NH₂
    Purity≥90% by HPLC
    SolubilityH₂O (1 mg/ml)
    Storage -20°C
    Hygroscopic
    Do Not Freeze Ok to freeze
    Special InstructionsFollowing recosntitution, aliquot and freeze (-20°C). Stock solutions are stable for 1-2 weeks at -20°C.
    Toxicity Standard Handling
    ReferencesFotouhi, N., et al. 1994. J. Biol. Chem. 269, 30227.
    Hanglow, A.C., et al. 1993. Agents Actions 39, C148.
    Citation
  • Anthony R. White, et al. (2006) Degradation of the alzheimer disease amyloid -peptide by metal-dependent up-regulation of metalloprotease activity. journal of Biological Chemistry 281, 17670-17680.