数量	产品目录编号	订购说明	数量 / 包装	公开价
			96-Well Plate

数量	产品目录编号	订购说明	数量 / 包装	公开价
	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

444251 Sigma-AldrichMMP-2/MMP-9 Inhibitor III - Calbiochem

The MMP-2/MMP-9 Inhibitor III controls the biological activity of MMP-2/MMP-9. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

MMP-2/MMP-9 Inhibitor III - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书
参考
Data Sheet

Primary Target: MMP-2, MMP-9

Recommended Products

概述

Replacement Information

重要规格表

Empirical Formula
C₅₂H₇₁N₁₃O₁₄S₂

Products

产品目录编号	包装	数量 / 包装
444251-1MGCN	塑胶安瓿;塑胶针药瓶	1 mg	添加到收藏夹添加到收藏夹添加到我的收藏夹

Description
Overview	A hydrophobic cyclic peptide that acts as a potent inhibitor of MMP-2 and MMP-9 (IC₅₀ = 10 µM). Inhibits the migration of human endothelial cells and tumor cells, and prevents tumor growth and invasion in animal models. Also, phage that display this peptide specifically targets angiogenic blood vessels in vivo.
Catalogue Number	444251
Brand Family	Calbiochem®

References
References	Medina, O.P., et al. 2001. Cancer Res. 61, 3978. Koivunen, E., et al. 1999. Nat. Biotechnology 17, 768.

Product Information
ATP Competitive	N
Declaration	Sold under license of U.S. Patent 6,624,144.
Form	White lyophilized solid
Formulation	Supplied as a trifluoroacetate salt.
Hill Formula	C₅₂H₇₁N₁₃O₁₄S₂
Chemical formula	C₅₂H₇₁N₁₃O₁₄S₂
Hygroscopic	Hygroscopic
Reversible	N
Quality Level	MQ100

Applications

Biological Information
Primary Target	MMP-2, MMP-9
Primary Target IC<sub>50</sub>	10 µM against MMP-2 and MMP-9
Purity	≥97% by HPLC

Physicochemical Information
Cell permeable	N
Peptide Sequence	H-Cys¹-Thr-Thr-His-Trp-Gly-Phe-Thr-Leu-Cys¹⁰-OH (cyclic: 1→ 10)

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Ambient Temperature Only
Toxicity	Standard Handling
Storage	-20°C
Hygroscopic	Hygroscopic
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze at -20°C. Stock solutions are stable for up to 2 months at -20°C.

Packaging Information
Packaged under inert gas	Packaged under inert gas

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
444251-1MGCN	04055977186512

Documentation

MMP-2/MMP-9 Inhibitor III - Calbiochem MSDS

职位
物料安全数据表 (MSDS)

MMP-2/MMP-9 Inhibitor III - Calbiochem 分析证书

标题	批号
444251	输入批号

参考

参考信息概述
Medina, O.P., et al. 2001. Cancer Res. 61, 3978. Koivunen, E., et al. 1999. Nat. Biotechnology 17, 768.

数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	06-August-2008 RFH
Description	A cyclic peptide that acts as a potent inhibitor of MMP-2 (gelatinase A; IC₅₀ = 10 µM) and MMP-9 (gelatinase B; IC₅₀ = 10 µM). Inhibits the migration of human endothelial cells and tumor cells, and prevents tumor growth and invasion in animal models.
Form	White lyophilized solid
Formulation	Supplied as a trifluoroacetate salt.
Intert gas (Yes/No)	Packaged under inert gas
Chemical formula	C₅₂H₇₁N₁₃O₁₄S₂
Peptide Sequence	H-Cys¹-Thr-Thr-His-Trp-Gly-Phe-Thr-Leu-Cys¹⁰-OH (cyclic: 1→ 10)
Purity	≥97% by HPLC
Solubility	H₂O (5 mg/ml)
Storage	-20°C Hygroscopic
Do Not Freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze at -20°C. Stock solutions are stable for up to 2 months at -20°C.
Toxicity	Standard Handling
References	Medina, O.P., et al. 2001. Cancer Res. 61, 3978. Koivunen, E., et al. 1999. Nat. Biotechnology 17, 768.

种类

Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Proteases Inhibitors > Matrix Metalloproteinase (MMP) Inhibitors

此产品已添加到您的购物车。