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444244 MMP-2 Inhibitor I - CAS 10335-69-0 - Calbiochem

The MMP-2 Inhibitor I, also referenced under CAS 10335-69-0, controls the biological activity of MMP-2. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

同义词: cis-9-Octadecenoyl-N-hydroxylamide, Oleoyl-N-hydroxylamide, OA-Hy

Primary Target: MMP-2
444244
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概述

Replacement Information

重要规格表

CAS #Empirical Formula
10335-69-0C₁₈H₃₅NO₂

Products

产品目录编号包装 数量 / 包装
444244-10MGCN 塑胶安瓿;塑胶针药瓶 10 mg
Description
OverviewA cell-permeable, potent inhibitor of MMP-2 that acts in a dose-dependent manner (Ki = 1.7 µM).
Catalogue Number444244
Brand Family Calbiochem®
Synonymscis-9-Octadecenoyl-N-hydroxylamide, Oleoyl-N-hydroxylamide, OA-Hy
References
ReferencesBerton, A., et. al. 2001. J. Biol. Chem. 276, 20458.
Emonard, H., et al. 1999. Ann. N.Y. Acad. Sci. 878, 647.
Product Information
CAS number10335-69-0
ATP CompetitiveN
FormWhite solid
Hill FormulaC₁₈H₃₅NO₂
Chemical formulaC₁₈H₃₅NO₂
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetMMP-2
Primary Target K<sub>i</sub>1.7 mM
Purity≥98% by HPLC
Physicochemical Information
Cell permeableY
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Blue Ice Only
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsUnstable in solution; reconstitute just prior to use.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
产品目录编号 GTIN
444244-10MGCN 04055977186468

Documentation

MMP-2 Inhibitor I - CAS 10335-69-0 - Calbiochem MSDS

职位

物料安全数据表 (MSDS) 

MMP-2 Inhibitor I - CAS 10335-69-0 - Calbiochem 分析证书

标题批号
444244

参考

参考信息概述
Berton, A., et. al. 2001. J. Biol. Chem. 276, 20458.
Emonard, H., et al. 1999. Ann. N.Y. Acad. Sci. 878, 647.

引用

标题
  • Anthony R. White, et al. (2006) Degradation of the alzheimer disease amyloid -peptide by metal-dependent up-regulation of metalloprotease activity. journal of Biological Chemistry 281, 17670-17680.
  • Michelle K.Y. Siu and C. Yan Cheng. (2004) Interactions of proteases, protease inhibitors, and the β1 integrin/laminin γ3 protein complex in the regulation of ectoplasmic specialization dynamics in the rat testis. Biology of Reproduction 70, 945-964.
  • Feng Zheng, et al. (2004) Development of albuinuria and glomerular lesions in normoglycemic B6 recepients of db/db mice bone marrow. Diabetes 53, 2420-2427.
    		•
    数据表

    Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

    Revision14-November-2023 JSW
    Synonymscis-9-Octadecenoyl-N-hydroxylamide, Oleoyl-N-hydroxylamide, OA-Hy
    DescriptionPotent inhibitor of MMP-2 (gelatinase A). Inhibits MMP-2 in a dose dependent manner (Ki = 1.7 µM)
    FormWhite solid
    Intert gas (Yes/No) Packaged under inert gas
    CAS number10335-69-0
    Chemical formulaC₁₈H₃₅NO₂
    Structure formulaStructure formula
    Purity≥98% by HPLC
    SolubilityDMSO (2 mg/ml) or Ethanol (3 mg/ml)
    Storage Protect from light
    -20°C
    Do Not Freeze Ok to freeze
    Special InstructionsUnstable in solution; reconstitute just prior to use.
    Toxicity Standard Handling
    ReferencesBerton, A., et. al. 2001. J. Biol. Chem. 276, 20458.
    Emonard, H., et al. 1999. Ann. N.Y. Acad. Sci. 878, 647.
    Citation
  • Anthony R. White, et al. (2006) Degradation of the alzheimer disease amyloid -peptide by metal-dependent up-regulation of metalloprotease activity. journal of Biological Chemistry 281, 17670-17680.
  • Michelle K.Y. Siu and C. Yan Cheng. (2004) Interactions of proteases, protease inhibitors, and the β1 integrin/laminin γ3 protein complex in the regulation of ectoplasmic specialization dynamics in the rat testis. Biology of Reproduction 70, 945-964.
  • Feng Zheng, et al. (2004) Development of albuinuria and glomerular lesions in normoglycemic B6 recepients of db/db mice bone marrow. Diabetes 53, 2420-2427.
    		•