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14-651M MARK1 Protein, active, 250 µg

Active, N-terminal 6His-tagged, recombinant, human MARK1, amino acids 2-end. For use in Kinase Assays.

14-651M
250 µg  Also available in 10 μg size (cat#14-651) and in bulk (cat# 14-651-K).
Purchase on Sigma-Aldrich

概述

Replacement Information
Description
Catalogue Number14-651M
Brand Family Upstate
Trade Name
  • Upstate
DescriptionMARK1 Protein, active, 250 µg
OverviewN-terminal 6His-tagged, recombinant, human MARK1, amino acids 2-end.
References
Product Information
Quality LevelMQ300
Applications
ApplicationActive, N-terminal 6His-tagged, recombinant, human MARK1, amino acids 2-end. For use in Kinase Assays.
Key Applications
  • Kinase Assay
Biological Information
SourceHuman MARK1 expressed by baculovirus in Sf21 insect cells.
Specific ActivityFor Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Entrez Gene Number
Gene Symbol
  • MARK1
  • KIAA1477
  • MGC126512
  • MGC126513
  • MARK
Protein TargetMARK1
Purification MethodNi2+/NTA-agarose
Target Sub-FamilyCAMK
UniProt Number
UniProt SummaryFUNCTION: SwissProt: Q9P0L2 # May play a role in cytoskeletal stability (By similarity).
COFACTOR: Magnesium.
SIZE: 795 amino acids; 89003 Da
SUBCELLULAR LOCATION: Cytoplasm (By similarity). Note=Appears to localize to an intracellular network (By similarity).
TISSUE SPECIFICITY: Highly expressed in heart, skeletal muscle, brain, fetal brain and fetal kidney.
SIMILARITY: SwissProt: Q9P0L2 ## Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. MARK subfamily. & Contains 1 KA1 (kinase-associated) domain. & Contains 1 protein kinase domain. & Contains 1 UBA domain.
Molecular Weight92.7kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assuranceroutinely evaluated by phosphorylation of CHKtide (12-373).
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions6 months at -70°C
Packaging Information
Material Size250 µg
Material PackageAlso available in 10 μg size (cat#14-651) and in bulk (cat# 14-651-K).
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
产品目录编号 GTIN
14-651M 04053252585531

Documentation