Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

428021 Latrunculin A, Latrunculia magnifica - CAS 76343-93-6 - Calbiochem

428021
Purchase on Sigma-Aldrich

概述

Replacement Information

重要规格表

CAS #Empirical Formula
76343-93-6C₂₂H₃₁NO₅S

Products

产品目录编号包装 数量 / 包装
428021-100UGCN 塑胶安瓿;塑胶针药瓶 100 μg
Description
OverviewA cell-permeable marine toxin that disrupts microfilament organization in cultured cells by the formation of a 1:1 complex with monomeric G-actin (Kd = 200 nM). Also a potent inhibitor of microfilament-mediated processes in sperm, eggs, and embryos. A 1 mM (50 µg/119 µl) solution of Latrunculin A, Latrunculia magnifica Cat. No. 428026 in DMSO is also available.
Catalogue Number428021
Brand Family Calbiochem®
References
ReferencesAyscough, K.R., et al. 1997. J. Cell Biol. 137, 399.
Spector, I., et al. 1989. Cell Motil. Cytoskeleton 13, 127.
Coue, M., et al. 1987. FEBS Lett. 213, 316.
Schatten, G., et al. 1986. Exp. Cell Res. 166, 191.
Spector, I., et al. 1983. Science 219, 493.
Product Information
CAS number76343-93-6
ATP CompetitiveN
FormWhite solid
Hill FormulaC₂₂H₃₁NO₅S
Chemical formulaC₂₂H₃₁NO₅S
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetG-actin
Primary Target IC<sub>50</sub>Kd = 200 nM in formation of a 1:1 complex with monomeric G-actin
Purity≥95% by HPLC
Physicochemical Information
Cell permeableY
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R PhraseR: 20/21/22

Harmful by inhalation, in contact with skin and if swallowed.
S PhraseS: 36

Wear suitable protective clothing.
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Harmful
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
产品目录编号 GTIN
428021-100UGCN 07790788050214

Documentation

Latrunculin A, Latrunculia magnifica - CAS 76343-93-6 - Calbiochem MSDS

职位

物料安全数据表 (MSDS) 

Latrunculin A, Latrunculia magnifica - CAS 76343-93-6 - Calbiochem 分析证书

标题批号
428021

参考

参考信息概述
Ayscough, K.R., et al. 1997. J. Cell Biol. 137, 399.
Spector, I., et al. 1989. Cell Motil. Cytoskeleton 13, 127.
Coue, M., et al. 1987. FEBS Lett. 213, 316.
Schatten, G., et al. 1986. Exp. Cell Res. 166, 191.
Spector, I., et al. 1983. Science 219, 493.
数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision29-March-2024 JSW
DescriptionA cell-permeable marine toxin from the Red Sea sponge Latrunculia magnifica that disrupts microfilament organization in cultured cells by the formation of a 1:1 complex with monomeric G-actin (Kd = 200 nM). Also a potent inhibitor of microfilament-mediated processes in sperm, eggs, and embryos.
FormWhite solid
Intert gas (Yes/No) Packaged under inert gas
CAS number76343-93-6
Chemical formulaC₂₂H₃₁NO₅S
Structure formulaStructure formula
Purity≥95% by HPLC
SolubilityDMSO (25 mg/ml)
Storage Protect from light
-20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Harmful
Merck USA index14, 8378
ReferencesAyscough, K.R., et al. 1997. J. Cell Biol. 137, 399.
Spector, I., et al. 1989. Cell Motil. Cytoskeleton 13, 127.
Coue, M., et al. 1987. FEBS Lett. 213, 316.
Schatten, G., et al. 1986. Exp. Cell Res. 166, 191.
Spector, I., et al. 1983. Science 219, 493.