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108396 色胺酸

概述

Replacement Information

重要规格表

CAS #EC号Hill配方摩尔质量级别值
73-22-3200-795-6C₁₁H₁₂N₂O₂204.23 g/molPh Eur,BP,JP,USP

Products

产品目录编号包装 数量 / 包装
1.08396.1000 塑胶瓶 1 kg
描述
产品目录编号108396
同义词Trp
参考
产品信息
CAS号73-22-3
EC号200-795-6
级别Ph Eur,BP,JP,USP
Hill配方C₁₁H₁₂N₂O₂
Molar Mass204.23 g/mol
HS代码2933 99 99
结构配方图像结构配方图像
Quality LevelMQ500
应用
生物信息
理化信息
熔点290 °C (分解)
pH值5.5 - 7 (1 g/l, H₂O, 25 °C)
容积密度400 kg/m3
溶解度10 g/l
尺寸
材料信息
毒性学信息
LD 50口服LD50 Rat 16000 mg/kg
GHS安全信息
RTECSYN6130000
储存类别10 - 13 其它液体及固体
WGKWGK 1 轻度的水危害
一次性3
反应性相对较低的有机物必须被收集在第A类, 如果被卤化则在第B类, 如果为固体残留物则归在第C类.
安全信息
产品使用声明
储存和货运信息
储存于 +2°C 到 +30°C储存.
包装信息
运输信息
补充信息
规格
Assay (perchloric acid titration, calculated on dried substance)98.5 - 101.0 %
Identity (IR-spectrum)passes test
Identity (specific rotation)passes test
Appearancewhite to almost white, crystalline or amorphous powder
Appearance of solution (10 g/l, Hydrochloric acid 1 mol/l)clear and not more intense in color than reference solution BY₆
Appearance of solution (20 g/l, hydrochloric acid 2 mol/l)clear
pH (10 g/l, CO₂-free water)5.5 - 6.4
Spec. rotation (α 20/D, 10 g/l, water, calc. on dried substance)-30.0 to -33.0
Spec. rotation (α 25/D, 10 g/l, water, calc. on dried substance)-29.4 to -32.8
Spec. rotation (α 20/D, 10 g/l, water, previously dried substance)-30.0 to -33.0
Chloride (Cl)≤ 200 ppm
Sulfate (SO₄)≤ 200 ppm
Heavy metals (as Pb)≤ 20 ppm
Fe (Iron)≤ 20 ppm
As (Arsenic)≤ 2 ppm
Ninhydrin-positive substances (LC) (any ninhydrin-positive impurity)≤ 0.2 %
Ninhydrin-positive substances (LC) (ammonium (570 nm))≤ 0.02 %
Ninhydrin-positive substances (LC) (total impurities)≤ 0.5 %
Related substances (HPLC)passes test
Impurity A ((1,1‘-ethylidenebistryptophan) Peak-E) (acc. to Ph Eur)≤ 10 ppm
Sum of impurities with RT < tryptophan-peak (acc. to Ph Eur)≤ 100 ppm
Sum of impurities with RT > tryptophan-peak and up to1,8 times the RT ofacetyltryptophan (acc. to Ph Eur)≤ 300 ppm
Impurity A ((1,1‘-ethylidenebistryptophan) Peak-E) (acc. to USP)≤ 10 ppm
Sum of impurities with RT < tryptophan-peak (acc. to USP)≤ 100 ppm
Sum of impurities with RT > tryptophan-peak, without tryptophan-peak andpeak of „Related Compound B“ (N-acetyltryptophan) (acc. to USP)≤ 300 ppm
Related substances (TLC)passes test
Residual solvents (ICH (Q3C))excluded by manufacturing process
Sulfated ash (600 °C)≤ 0.1 %
Loss on drying (105 °C; 3 h)≤ 0.30 %
Bacterial endotoxins≤ 10 I.U./g
Microbiological test (total aerobic microbial count (TAMC))≤ 100 CFU/g
Microbiological test (total yeast and mould count (TYMC))≤ 100 CFU/g
Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
Corresponds to Ph. Eur., BP, JP, USP.
Global Trade Item Number
产品目录编号 GTIN
1.08396.1000 04022536104003

Documentation

Material Qualification Dossier

标题版本
9.0

Quality Management Dossier (Open Access)

Title

Operational Excellence Dossier

Title

色胺酸 MSDS

职位

物料安全数据表 (MSDS) 

色胺酸 分析证书

产品货号 包装规格批号
1.08396.1000 塑胶瓶PDF文档规格

证书

标题