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IF014 Interferon-β Protein, Recombinant human

IF014
100000 units  
Purchase on Sigma-Aldrich

概述

Replacement Information

重要规格表

Key ApplicationsSpeciesSourcePurity
CULTHuman cDNA obtained from human fibroblast mRNA expressed in CHO cells.> / = 95%, one N-glycosylation site
Description
Catalogue NumberIF014
ReplacesIF008
Brand Family Chemicon®
Trade Name
  • Chemicon
DescriptionInterferon-β Protein, Recombinant human
OverviewRecombinant Human Interferon Beta 1a (Hu-IFNbeta 1a). Molecular weight is ~23 kDa.
Alternate Names
  • Fibroblast Interferon
References
Product Information
PresentationFrozen liquid in 50 mM NaOAc, pH 5.5, containing 0.1% BSA.
Quality LevelMQ100
Applications
ApplicationRecombinant Human Interferon Beta 1a (Hu-IFNbeta 1a).
Key Applications
  • Cell Culture
Biological Information
Concentration1 x 106 units/mL
Purity> / = 95%, one N-glycosylation site
SourcecDNA obtained from human fibroblast mRNA expressed in CHO cells.
Specific ActivitySPECIFIC ACTIVITY: 3.99 x 108 units/mg <br /><br />BIOACTIVITY: Determined by assaying inhibition of virus-induced cytopathic effect. In this antiviral assay for interferon, about 1 unit/ml of interferon is the quantity necessary to produce a cytopathic effect of 50%. The units are determined with respect to the international reference standard for human interferon beta (Hu-IFNbeta) provided by the National Institutes of Health. Unit of activity measured on VERO cells with vesicular stomatitis virus (VSV).
Entrez Gene Number
Gene Symbol
  • IFNB1
  • IFN-beta
  • IFF
  • IFB
  • IFNB
  • MGC96956
UniProt Number
UniProt SummaryFUNCTION: SwissProt: P01574 # Has antiviral, antibacterial and anticancer activities.
SIZE: 187 amino acids; 22294 Da
SUBUNIT: Monomer.
SUBCELLULAR LOCATION: Secreted.
SIMILARITY: SwissProt: P01574 ## Belongs to the alpha/beta interferon family.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsAfter receipt, this product should be kept at -70°C or below for retention of full activity.
Thaw product vial by incubation cold tap water until just thawed. Thawed IFNβ should be
stored in working aliquots at -70°C for up to six months. Avoid multiple freeze/thaw cycles.
Refreezing should be done on dry ice or in a dry ice/alcohol bath. Further dilution of the
product should be in buffers containing protein such as 0.1% bovine serum albumin (BSA).
Packaging Information
Material Size100000 units
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
产品目录编号 GTIN
IF014 04053252470646

Documentation

Interferon-β Protein, Recombinant human MSDS

职位

物料安全数据表 (MSDS) 

Interferon-β Protein, Recombinant human 分析证书

标题批号
Fibroblast Interferon (Accession # V00534) - 2089401 2089401
HUMAN INTERFERON BETA 1A 2886680
HUMAN INTERFERON BETA 1A 2886681
HUMAN INTERFERON BETA 1A 3128880
HUMAN INTERFERON BETA 1A 2475636
HUMAN INTERFERON BETA 1A 2901714
HUMAN INTERFERON BETA 1A 2960612
HUMAN INTERFERON BETA 1A 3086586
HUMAN INTERFERON BETA 1A 3104266
HUMAN INTERFERON BETA 1A 2999900

数据表

标题
HUMAN INTERFERON BETA 1A